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231225s2022 xx |||||o 00| ||eng c |
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|a 10.1016/j.plaphy.2022.02.018
|2 doi
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|a pubmed25n1125.xml
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|a (NLM)35247693
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|a DE-627
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|a eng
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|a Mendes, Gabriela Galvão Machado
|e verfasserin
|4 aut
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|a Inhibiting tricin biosynthesis improves maize lignocellulose saccharification
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 23.03.2022
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|a Date Revised 23.03.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2022 Elsevier Masson SAS. All rights reserved.
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|a Lignin is a technological bottleneck to convert polysaccharides into fermentable sugars, and different strategies of genetic-based metabolic engineering have been applied to improve biomass saccharification. Using maize seedlings grown hydroponically for 24 h, we conducted a quick non-transgenic approach with five enzyme inhibitors of the lignin and tricin pathways. Two compounds [3,4-(methylenedioxy)cinnamic acid: MDCA and 2,4-pyridinedicarboxylic acid: PDCA] revealed interesting findings on root growth, lignin composition, and saccharification. By inhibiting hydroxycinnamoyl-CoA ligase, a key enzyme of phenylpropanoid pathway, MDCA decreased the lignin content and improved saccharification, but it decreased root growth. By inhibiting flavone synthase, a key enzyme of tricin biosynthesis, PDCA decreased total lignin content and improved saccharification without affecting root growth. PDCA was three-fold more effective than MDCA, suggesting that controlling lignin biosynthesis with enzymatic inhibitors may be an attractive strategy to improve biomass saccharification
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|a Journal Article
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|a Biofuels
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|a Flavone synthase
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|a Hydroxycinnamoyl-CoA ligase. Lignin
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|a Recalcitrant biomass
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|a Zea mays
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|a Flavonoids
|2 NLM
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|a lignocellulose
|2 NLM
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|a 11132-73-3
|2 NLM
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|a Lignin
|2 NLM
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|a 9005-53-2
|2 NLM
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|a tricin
|2 NLM
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|a D51JZL38TQ
|2 NLM
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|a Mota, Thatiane Rodrigues
|e verfasserin
|4 aut
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|a Bossoni, Gabriela Ellen Barreto
|e verfasserin
|4 aut
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|a Marchiosi, Rogério
|e verfasserin
|4 aut
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|a Oliveira, Dyoni Matias de
|e verfasserin
|4 aut
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|a Constantin, Rodrigo Polimeni
|e verfasserin
|4 aut
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|a Dos Santos, Wanderley Dantas
|e verfasserin
|4 aut
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|a Ferrarese-Filho, Osvaldo
|e verfasserin
|4 aut
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|i Enthalten in
|t Plant physiology and biochemistry : PPB
|d 1991
|g 178(2022) vom: 01. Mai, Seite 12-19
|w (DE-627)NLM098178261
|x 1873-2690
|7 nnas
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|g volume:178
|g year:2022
|g day:01
|g month:05
|g pages:12-19
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|u http://dx.doi.org/10.1016/j.plaphy.2022.02.018
|3 Volltext
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