Comparison of three hematocrit measurement methods in the southern white rhinoceros (Ceratotherium simum simum)

© 2022 The Authors. Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology.

Bibliographische Detailangaben
Veröffentlicht in:Veterinary clinical pathology. - 1975. - 51(2022), 2 vom: 01. Juni, Seite 225-230
1. Verfasser: Steyrer, Christof (VerfasserIn)
Weitere Verfasser: Pohlin, Friederike, Meyer, Leith C R, Buss, Peter, Hooijberg, Emma H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Veterinary clinical pathology
Schlagworte:Journal Article Abaxis HM5 EPOC method comparison packed cell volume point-of-care
LEADER 01000naa a22002652 4500
001 NLM337754209
003 DE-627
005 20231225235130.0
007 cr uuu---uuuuu
008 231225s2022 xx |||||o 00| ||eng c
024 7 |a 10.1111/vcp.13076  |2 doi 
028 5 2 |a pubmed24n1125.xml 
035 |a (DE-627)NLM337754209 
035 |a (NLM)35244231 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Steyrer, Christof  |e verfasserin  |4 aut 
245 1 0 |a Comparison of three hematocrit measurement methods in the southern white rhinoceros (Ceratotherium simum simum) 
264 1 |c 2022 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 03.06.2022 
500 |a Date Revised 31.07.2022 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a © 2022 The Authors. Veterinary Clinical Pathology published by Wiley Periodicals LLC on behalf of American Society for Veterinary Clinical Pathology. 
520 |a BACKGROUND: Hematocrit (HCT) determination is an integral part of health and disease assessments in captive and wild white rhinoceroses. Several affordable automated hematology analyzers have been developed for in-clinic and field use and have the advantage of being able to measure a large number of additional measurands. However, the accuracy of these analyzers for rhinoceros HCT measurements has not yet been investigated 
520 |a OBJECTIVES: We aimed to compare the HCT results generated by the EPOC portable analyzer system and the Abaxis VetScan HM5 with the gold standard of a manual packed cell volume (PCV) measured using the microhematocrit method 
520 |a METHODS: Hematocrits were measured with the EPOC and the Abaxis VetScan HM5 (bovine setting) and compared with the PCVs of 69 white rhinoceros whole blood samples. Results were compared using Bland-Altman difference plots and Passing-Bablok regression analysis. A total allowable analytical error of 10% was set as the performance goal 
520 |a RESULTS: A significant positive bias, with a mean of 7.7% for the EPOC and 17.9% for the Abaxis, was found compared with the manual PCV method 
520 |a CONCLUSIONS: The allowable error goal of 10% was not exceeded with the EPOC analyzer. Although not analytically equivalent to the gold standard, the EPOC results could therefore be used as approximations in critical situations where manual measurements cannot be performed. The Abaxis exceeded this allowable error and overestimated HCTs in rhinoceroses. Therefore, method-specific reference intervals should be used 
650 4 |a Journal Article 
650 4 |a Abaxis HM5 
650 4 |a EPOC 
650 4 |a method comparison 
650 4 |a packed cell volume 
650 4 |a point-of-care 
700 1 |a Pohlin, Friederike  |e verfasserin  |4 aut 
700 1 |a Meyer, Leith C R  |e verfasserin  |4 aut 
700 1 |a Buss, Peter  |e verfasserin  |4 aut 
700 1 |a Hooijberg, Emma H  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Veterinary clinical pathology  |d 1975  |g 51(2022), 2 vom: 01. Juni, Seite 225-230  |w (DE-627)NLM098159984  |x 1939-165X  |7 nnns 
773 1 8 |g volume:51  |g year:2022  |g number:2  |g day:01  |g month:06  |g pages:225-230 
856 4 0 |u http://dx.doi.org/10.1111/vcp.13076  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 51  |j 2022  |e 2  |b 01  |c 06  |h 225-230