Lab-on-a-Contact Lens : Recent Advances and Future Opportunities in Diagnostics and Therapeutics

Bibliographische Detailangaben
Veröffentlicht in:	Advanced materials (Deerfield Beach, Fla.). - 1998. - 34(2022), 24 vom: 07. Juni, Seite e2108389
1. Verfasser:	Zhu, Yangzhi (VerfasserIn)
Weitere Verfasser:	Li, Shaopei, Li, Jinghang, Falcone, Natashya, Cui, Qingyu, Shah, Shilp, Hartel, Martin C, Yu, Ning, Young, Patric, de Barros, Natan Roberto, Wu, Zhuohong, Haghniaz, Reihaneh, Ermis, Menekse, Wang, Canran, Kang, Heemin, Lee, Junmin, Karamikamkar, Solmaz, Ahadian, Samad, Jucaud, Vadim, Dokmeci, Mehmet R, Kim, Han-Jun, Khademhosseini, Ali
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2022
Zugriff auf das übergeordnete Werk:	Advanced materials (Deerfield Beach, Fla.)
Schlagworte:	Journal Article Review bioelectronics biosensors contact lens diagnostics integrated systems personalized healthcare therapeutics wearable electronics mehr... Glucose IY9XDZ35W2

Beschreibung
Zusammenfassung:	© 2022 Wiley-VCH GmbH. The eye is one of the most complex organs in the human body, containing rich and critical physiological information (e.g., intraocular pressure, corneal temperature, and pH) as well as a library of metabolite biomarkers (e.g., glucose, proteins, and specific ions). Smart contact lenses (SCLs) can serve as a wearable intelligent ocular prosthetic device capable of noninvasive and continuous monitoring of various essential physical/biochemical parameters and drug loading/delivery for the treatment of ocular diseases. Advances in SCL technologies and the growing public interest in personalized health are accelerating SCL research more than ever before. Here, the current status and potential of SCL development through a comprehensive review from fabrication to applications to commercialization are discussed. First, the material, fabrication, and platform designs of the SCLs for the diagnostic and therapeutic applications are discussed. Then, the latest advances in diagnostic and therapeutic SCLs for clinical translation are reviewed. Later, the established techniques for wearable power transfer and wireless data transmission applied to current SCL devices are summarized. An outlook, future opportunities, and challenges for developing next-generation SCL devices are also provided. With the rise in interest of SCL development, this comprehensive and essential review can serve as a new paradigm for the SCL devices
Beschreibung:	Date Completed 17.06.2022 Date Revised 30.08.2024 published: Print-Electronic Citation Status MEDLINE
ISSN:	1521-4095
DOI:	10.1002/adma.202108389