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231225s2021 xx |||||o 00| ||eng c |
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|a 10.37616/2212-5043.1269
|2 doi
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|a (NLM)35083118
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|a DE-627
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|a eng
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|a Kumar, Dileep
|e verfasserin
|4 aut
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|a Predictors of 6-month Mortality in Patients with Non-ST Elevation Acute Coronary Syndrome
|b A Study in Pakistani Population
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Revised 30.04.2022
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|a published: Electronic-eCollection
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|a Citation Status PubMed-not-MEDLINE
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|a © 2021 Saudi Heart Association.
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|a OBJECTIVES: For Southern Asian countries like Pakistan, there is inadequate evidence of risk factors associated with mortality in patients suffering from acute coronary syndrome (ACS), especially non-ST elevation ACS (NSTE-ACS) cases. Therefore, aim of this study was to evaluate predictors of 6-months mortality of patients presenting with NSTE-ACS
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|a METHODS: For this prospective observational study we recruited adult patients diagnosed with NSTE-ACS at a tertiary cardiac center. All he patients were followed-up after six months and survival status was recorded. Logistic regression analysis was performed for six-month mortality and odds ratio (OR) and 95% confidence interval (CI) were reported
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|a RESULTS: Six-month follow-up was successful for 280 patients. On univariate analysis age >65 years, increased heart rate, cardiac arrest at presentation, Killip class II-IV at presentation, and diabetes were found to be associated with increased risk of 6-months mortality with OR [95% CI] of 4.27 [1.9-9.58], 1.25 [1.1-1.41], 139.44 [16.9-1150.78], 68.45 [7.88-594.41], and 2.35 [1.06-5.22] respectively. On multivariable analysis Killip class II-IV at presentation, thrombolysis in myocardial infarction (TIMI) score of >4, and global registry of acute coronary events (GRACE) score ≥150 were found to be independent predictors of mortality after six months of NSTE-ACS with adjusted OR of 32.93 [2.65-408.8], 3.42 [1.35-8.66], and 8.43 [3.33-21.38] respectively
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|a CONCLUSIONS: For patients with NSTE-ACS, our study showed seven clinical parameters to be associated with an increased risk of 6-month mortality. These included increasing age, increased heart rate, cardiac arrest at presentation, Killip class II-IV, diabetes, TIMI score of >4 and GRACE score of >150. Thereby aiding clinicians to apply strategic and precise interventions in monitoring these patients accordingly
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|a Journal Article
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|a 6-month mortality
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|a Acute coronary syndrome
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|a Non-ST elevation ACS
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|a Predictors
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|a Saghir, Tahir
|e verfasserin
|4 aut
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|a Kumar, Rajesh
|e verfasserin
|4 aut
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|a Sial, Jawaid Akbar
|e verfasserin
|4 aut
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|a Khan, Kamran Ahmed
|e verfasserin
|4 aut
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|a Shah, Jehangir Ali
|e verfasserin
|4 aut
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|a Karim, Musa
|e verfasserin
|4 aut
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|a Mueed, Abdul
|e verfasserin
|4 aut
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|a Bai, Reeta
|e verfasserin
|4 aut
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|a Kumar, Hitesh
|e verfasserin
|4 aut
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|a Ali, Sajjad
|e verfasserin
|4 aut
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|a Kumari, Rekha
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of the Saudi Heart Association
|d 1999
|g 33(2021), 4 vom: 18., Seite 286-292
|w (DE-627)NLM098225227
|x 1016-7315
|7 nnas
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|g volume:33
|g year:2021
|g number:4
|g day:18
|g pages:286-292
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|u http://dx.doi.org/10.37616/2212-5043.1269
|3 Volltext
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|d 33
|j 2021
|e 4
|b 18
|h 286-292
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