Predictors of 6-month Mortality in Patients with Non-ST Elevation Acute Coronary Syndrome : A Study in Pakistani Population

© 2021 Saudi Heart Association.

Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 33(2021), 4 vom: 18., Seite 286-292
1. Verfasser: Kumar, Dileep (VerfasserIn)
Weitere Verfasser: Saghir, Tahir, Kumar, Rajesh, Sial, Jawaid Akbar, Khan, Kamran Ahmed, Shah, Jehangir Ali, Karim, Musa, Mueed, Abdul, Bai, Reeta, Kumar, Hitesh, Ali, Sajjad, Kumari, Rekha
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article 6-month mortality Acute coronary syndrome Non-ST elevation ACS Predictors
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520 |a OBJECTIVES: For Southern Asian countries like Pakistan, there is inadequate evidence of risk factors associated with mortality in patients suffering from acute coronary syndrome (ACS), especially non-ST elevation ACS (NSTE-ACS) cases. Therefore, aim of this study was to evaluate predictors of 6-months mortality of patients presenting with NSTE-ACS 
520 |a METHODS: For this prospective observational study we recruited adult patients diagnosed with NSTE-ACS at a tertiary cardiac center. All he patients were followed-up after six months and survival status was recorded. Logistic regression analysis was performed for six-month mortality and odds ratio (OR) and 95% confidence interval (CI) were reported 
520 |a RESULTS: Six-month follow-up was successful for 280 patients. On univariate analysis age >65 years, increased heart rate, cardiac arrest at presentation, Killip class II-IV at presentation, and diabetes were found to be associated with increased risk of 6-months mortality with OR [95% CI] of 4.27 [1.9-9.58], 1.25 [1.1-1.41], 139.44 [16.9-1150.78], 68.45 [7.88-594.41], and 2.35 [1.06-5.22] respectively. On multivariable analysis Killip class II-IV at presentation, thrombolysis in myocardial infarction (TIMI) score of >4, and global registry of acute coronary events (GRACE) score ≥150 were found to be independent predictors of mortality after six months of NSTE-ACS with adjusted OR of 32.93 [2.65-408.8], 3.42 [1.35-8.66], and 8.43 [3.33-21.38] respectively 
520 |a CONCLUSIONS: For patients with NSTE-ACS, our study showed seven clinical parameters to be associated with an increased risk of 6-month mortality. These included increasing age, increased heart rate, cardiac arrest at presentation, Killip class II-IV, diabetes, TIMI score of >4 and GRACE score of >150. Thereby aiding clinicians to apply strategic and precise interventions in monitoring these patients accordingly 
650 4 |a Journal Article 
650 4 |a 6-month mortality 
650 4 |a Acute coronary syndrome 
650 4 |a Non-ST elevation ACS 
650 4 |a Predictors 
700 1 |a Saghir, Tahir  |e verfasserin  |4 aut 
700 1 |a Kumar, Rajesh  |e verfasserin  |4 aut 
700 1 |a Sial, Jawaid Akbar  |e verfasserin  |4 aut 
700 1 |a Khan, Kamran Ahmed  |e verfasserin  |4 aut 
700 1 |a Shah, Jehangir Ali  |e verfasserin  |4 aut 
700 1 |a Karim, Musa  |e verfasserin  |4 aut 
700 1 |a Mueed, Abdul  |e verfasserin  |4 aut 
700 1 |a Bai, Reeta  |e verfasserin  |4 aut 
700 1 |a Kumar, Hitesh  |e verfasserin  |4 aut 
700 1 |a Ali, Sajjad  |e verfasserin  |4 aut 
700 1 |a Kumari, Rekha  |e verfasserin  |4 aut 
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