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231225s2022 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.1c02824
|2 doi
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|a pubmed24n1118.xml
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|a (DE-627)NLM335648371
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|a (NLM)35029992
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Kojima, Keiko
|e verfasserin
|4 aut
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|a Streptavidin-Conjugated Oxygen-Doped Single-Walled Carbon Nanotubes as Near-Infrared Labels for Immunoassays
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|c 2022
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 08.03.2022
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|a Date Revised 08.03.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Single-walled carbon nanotubes (CNTs) are promising candidates for near-infrared (NIR) fluorescent labels in diagnostic fields. We report a complex of oxygen-doped CNT (o-CNT) and streptavidin (SA) for preparing CNT-based NIR labels with a high reaction efficiency in immunoassays. This complex specifically binds to biotin molecules by conjugating a linker molecule of phospholipid polyethylene glycol (PL-PEG) to SA (o-CNT-SA). The immunoprecipitation reaction efficiency between o-CNT-SA and biotin reaches 79.3% when the surface of o-CNTs is uniformly covered with SA-conjugated PL-PEG. The strong affinity between SA and biotin is useful for preparing CNT-based sensitive NIR fluorescent labels
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Nanotubes, Carbon
|2 NLM
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|a Polyethylene Glycols
|2 NLM
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|a 3WJQ0SDW1A
|2 NLM
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|a Streptavidin
|2 NLM
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|a 9013-20-1
|2 NLM
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|a Oxygen
|2 NLM
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|a S88TT14065
|2 NLM
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|a Iizumi, Yoko
|e verfasserin
|4 aut
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|a Zhang, Minfang
|e verfasserin
|4 aut
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|a Okazaki, Toshiya
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 38(2022), 4 vom: 01. Feb., Seite 1509-1513
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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|g volume:38
|g year:2022
|g number:4
|g day:01
|g month:02
|g pages:1509-1513
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|u http://dx.doi.org/10.1021/acs.langmuir.1c02824
|3 Volltext
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