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|a 10.1016/j.clim.2021.108919
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|a eng
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|a Koga, Tomohiro
|e verfasserin
|4 aut
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|a Tissue resident cell processes determine organ damage in systemic lupus erythematosus
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|c 2022
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|a Text
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|a ƒaComputermedien
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|a Date Completed 25.02.2022
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|a Date Revised 25.02.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2021 Elsevier Inc. All rights reserved.
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|a Systemic lupus erythematosus (SLE) is an autoimmune disease that affects almost any organ. Multiple immunological abnormalities involving every domain of the immune system contribute to the expression of the disease. It is now recognized that elements of the immune system instigate processes in tissue resident cells which execute organ damage. Although correction of ongoing immune aberrations is important in the control of disease activity, targeting tissue specific injurious processes may prove desirable in limiting organ damage
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Immune responses
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|a Lupus nephritis
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|a Organ damage
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|a Systemic lupus erythematosus (SLE)
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|a Ichinose, Kunihiro
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|a Tsokos, George C
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|t Clinical immunology (Orlando, Fla.)
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