Smart Tumor Microenvironment-Responsive Nano-Prodrug for Disulfiram Toxification In Situ and the Exploration of Lethal Mechanisms in Cells
Disulfiram (DSF) is a clinical antialcoholism drug that has been confirmed to show anticancer bioactivity after chelating with Cu2+. Therefore, how to co-deliver DSF and Cu2+ to tumor tissues and generate a smart response to the tumor microenvironment (TME) are the focus of repurposing DSF for the e...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 38(2022), 1 vom: 11. Jan., Seite 584-592
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| 1. Verfasser: |
Zhang, Ying
(VerfasserIn) |
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| Weitere Verfasser: |
Qi, Guohua,
Qu, Xiaozhang,
Wang, Bo,
Ma, Kongshuo,
Jin, Yongdong |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2022
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Prodrugs
Copper
789U1901C5
Disulfiram
TR3MLJ1UAI |
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