|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM334392535 |
| 003 |
DE-627 |
| 005 |
20231225223619.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2022 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1016/j.plaphy.2021.11.041
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1114.xml
|
| 035 |
|
|
|a (DE-627)NLM334392535
|
| 035 |
|
|
|a (NLM)34902782
|
| 035 |
|
|
|a (PII)S0981-9428(21)00607-0
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Lima, Karollyny Roger Pereira
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Metabolomic profiles exhibit the influence of endoplasmic reticulum stress on sorghum seedling growth over time
|
| 264 |
|
1 |
|c 2022
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 11.01.2022
|
| 500 |
|
|
|a Date Revised 11.01.2022
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2021 Elsevier Masson SAS. All rights reserved.
|
| 520 |
|
|
|a Environmental stresses disturb the endoplasmic reticulum (ER) protein folding. However, primary metabolic responses induced by ER stress remain unclear. Thus, we investigated the morphophysiological and metabolomic changes under ER stress, induced by dithiothreitol (DTT) and tunicamycin (TM) treatments in sorghum seedlings from 24 to 96 h. The ER stress caused lipid peroxidation and increased the expression of SbBiP1, SbPDI, and SbIRE1. The development impairment was more pronounced in roots than in shoots as distinct metabolomic profiles were observed. DTT decreased root length, lateral roots, and root hair, while TM decreased mainly the root length. At 24 h, under ER stresses, the glutamic acid and o-acetyl-serine were biomarkers in the shoots. While homoserine, pyroglutamic acid, and phosphoric acid were candidates for roots. At the latest time (96 h), kestose and galactinol were key metabolites for shoots under DTT and TM, respectively. In roots, palatinose, trehalose, and alanine were common markers for DTT and TM late exposure. The accumulation of sugars such as arabinose and kestose occurred mainly in roots in the presence of DTT at a later time, which also inhibited glycolysis and the tricarboxylic acid cycle (TCA). Amino acid metabolism was induced, which also contributed TCA components decreasing, such as succinate in shoots and citrate in roots. Thus, our study may provide new insights into primary metabolism modulated by ER stress and seedling development
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Dithiothreitol
|
| 650 |
|
4 |
|a Gas chromatography
|
| 650 |
|
4 |
|a Mass spectrometry
|
| 650 |
|
4 |
|a Sorghum bicolor
|
| 650 |
|
4 |
|a Tunicamycin
|
| 650 |
|
7 |
|a Tunicamycin
|2 NLM
|
| 650 |
|
7 |
|a 11089-65-9
|2 NLM
|
| 650 |
|
7 |
|a Dithiothreitol
|2 NLM
|
| 650 |
|
7 |
|a T8ID5YZU6Y
|2 NLM
|
| 700 |
1 |
|
|a Cavalcante, Francisco Lucas Pacheco
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Paula-Marinho, Stelamaris de Oliveira
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Pereira, Isabelle Mary Costa
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Lopes, Lineker de Sousa
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Nunes, João Victor Serra
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Coutinho, Ítalo Antônio Cotta
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Gomes-Filho, Enéas
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Carvalho, Humberto Henrique de
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Plant physiology and biochemistry : PPB
|d 1991
|g 170(2022) vom: 01. Jan., Seite 192-205
|w (DE-627)NLM098178261
|x 1873-2690
|7 nnns
|
| 773 |
1 |
8 |
|g volume:170
|g year:2022
|g day:01
|g month:01
|g pages:192-205
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1016/j.plaphy.2021.11.041
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 170
|j 2022
|b 01
|c 01
|h 192-205
|