Topology-Dependent Interaction of Cyclic Poly(ethylene glycol) Complexed with Gold Nanoparticles against Bovine Serum Albumin for a Colorimetric Change

Unique physical and chemical properties arising from a polymer topology recently draw significant attention. In this study, cyclic poly(ethylene glycol) (c-PEG) was found to significantly interact with bovine serum albumin (BSA), suggested by nuclear magnetic resonance, dynamic light scattering, and...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 38(2022), 17 vom: 03. Mai, Seite 5286-5295
1. Verfasser: Oziri, Onyinyechukwu Justina (VerfasserIn)
Weitere Verfasser: Maeki, Masatoshi, Tokeshi, Manabu, Isono, Takuya, Tajima, Kenji, Satoh, Toshifumi, Sato, Shin-Ichiro, Yamamoto, Takuya
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Serum Albumin, Bovine 27432CM55Q Polyethylene Glycols 3WJQ0SDW1A Gold 7440-57-5
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520 |a Unique physical and chemical properties arising from a polymer topology recently draw significant attention. In this study, cyclic poly(ethylene glycol) (c-PEG) was found to significantly interact with bovine serum albumin (BSA), suggested by nuclear magnetic resonance, dynamic light scattering, and fluorescence spectroscopy. On the other hand, linear HO-PEG-OH and MeO-PEG-OMe showed no affinity. Furthermore, a complex of gold nanoparticles and c-PEG (AuNPs/c-PEG) attracted BSA to form aggregates, and the red color of the AuNPs dispersion evidently disappeared, whereas ones with linear PEG or without PEG did not demonstrate such a phenomenon. The interactions among BSA, AuNPs, and PEG were investigated by changing the incubation time and concentration of the components by using UV-Vis and fluorescence spectroscopy 
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700 1 |a Tokeshi, Manabu  |e verfasserin  |4 aut 
700 1 |a Isono, Takuya  |e verfasserin  |4 aut 
700 1 |a Tajima, Kenji  |e verfasserin  |4 aut 
700 1 |a Satoh, Toshifumi  |e verfasserin  |4 aut 
700 1 |a Sato, Shin-Ichiro  |e verfasserin  |4 aut 
700 1 |a Yamamoto, Takuya  |e verfasserin  |4 aut 
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