A Biocompatible Vibration-Actuated Omni-Droplets Rectifier with Large Volume Range Fabricated by Femtosecond Laser

Bibliographische Detailangaben
Veröffentlicht in:	Advanced materials (Deerfield Beach, Fla.). - 1998. - 34(2022), 12 vom: 07. März, Seite e2108567
1. Verfasser:	Zhang, Yiyuan (VerfasserIn)
Weitere Verfasser:	Li, Jing, Xiang, Le, Wang, Jinxing, Wu, Tao, Jiao, Yunlong, Jiang, Shaojun, Li, Chuanzong, Fan, Shengying, Zhang, Juan, Wu, Hao, Zhang, Yuxuan, Bian, Yucheng, Zhao, Kun, Peng, Yubin, Zhu, Wulin, Li, Jiawen, Hu, Yanlei, Wu, Dong, Chu, Jiaru, Wang, Zuankai
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2022
Zugriff auf das übergeordnete Werk:	Advanced materials (Deerfield Beach, Fla.)
Schlagworte:	Journal Article biomedical detection \| biomedical devices mechanical vibration omni-droplets rectifiers slippery ratchets

Beschreibung
Zusammenfassung:	© 2022 Wiley-VCH GmbH. High-performance droplet transport is crucial for diverse applications including biomedical detection, chemical micro-reaction, and droplet microfluidics. Despite extensive progress, traditional passive and active strategies are restricted to limited liquid types, small droplet volume ranges, and poor biocompatibilities. Moreover, more challenges occur for biological fluids due to large viscosity and low surface tension. Here, a vibration-actuated omni-droplets rectifier (VAODR) consisting of slippery ratchet arrays fabricated by femtosecond laser and vibration platforms is reported. Through the relative competition between the asymmetric adhesive resistance originating from the lubricant meniscus on the VAODR and the periodic inertial driving force originating from isotropic vibration, the fast (up to ≈60 mm s-1 ), programmable, and robust transport of droplets is achieved for a large volume range (0.05-2000 µL, Vmax /Vmin ≈ 40 000) and in various transport modes including transport of liquid slugs in tubes, programmable and sequential transport, and bidirectional transport. This VAODR is general to a high diversity of biological and medical fluids, and thus can be used for biomedical detection including ABO blood-group tests and anticancer drugs screening. These strategies provide a complementary and promising platform for maneuvering omni-droplets that are fundamental to biomedical applications and other high-throughput omni-droplet operation fields
Beschreibung:	Date Completed 01.04.2022 Date Revised 01.04.2022 published: Print-Electronic Citation Status MEDLINE
ISSN:	1521-4095
DOI:	10.1002/adma.202108567