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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.1c02080
|2 doi
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|a pubmed24n1111.xml
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|a eng
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|a Stucchi, Simone
|e verfasserin
|4 aut
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|a Squarate Cross-Linked Gelatin Hydrogels as Three-Dimensional Scaffolds for Biomedical Applications
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|c 2021
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 27.01.2022
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|a Date Revised 27.01.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Hydrogels are useful platforms as three-dimensional (3D) scaffolds for cell culture, drug-release systems, and regenerative medicine applications. Here, we propose a novel chemical cross-linking approach by the use of 3,4-diethoxy-3-cyclobutene-1,2-dione or diethyl squarate for the preparation of 5 and 10% w/v gelatin-based hydrogels. Hydrogels showed good swelling properties, and the 5% gelatin-based hydrogel proved suitable as a 3D cell culture scaffold for the chondrocyte cell line C28/I2. In addition, diffusion properties of different sized molecules inside the hydrogel were determined
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Hydrogels
|2 NLM
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|a Gelatin
|2 NLM
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|a 9000-70-8
|2 NLM
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|a Colombo, Danilo
|e verfasserin
|4 aut
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|a Guizzardi, Roberto
|e verfasserin
|4 aut
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|a D'Aloia, Alessia
|e verfasserin
|4 aut
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|a Collini, Maddalena
|e verfasserin
|4 aut
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|a Bouzin, Margaux
|e verfasserin
|4 aut
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|a Costa, Barbara
|e verfasserin
|4 aut
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|a Ceriani, Michela
|e verfasserin
|4 aut
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|a Natalello, Antonino
|e verfasserin
|4 aut
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|a Pallavicini, Piersandro
|e verfasserin
|4 aut
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|a Cipolla, Laura
|e verfasserin
|4 aut
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 37(2021), 48 vom: 07. Dez., Seite 14050-14058
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|x 1520-5827
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|g volume:37
|g year:2021
|g number:48
|g day:07
|g month:12
|g pages:14050-14058
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|u http://dx.doi.org/10.1021/acs.langmuir.1c02080
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