Steroidal alkaloids defence metabolism and plant growth are modulated by the joint action of gibberellin and jasmonate signalling

Steroidal alkaloids defence metabolism and plant growth are modulated by the joint action of gibberellin and jasmonate signalling

© 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 233(2022), 3 vom: 12. Feb., Seite 1220-1237
1. Verfasser: Panda, Sayantan (VerfasserIn)
Weitere Verfasser: Jozwiak, Adam, Sonawane, Prashant D, Szymanski, Jedrzej, Kazachkova, Yana, Vainer, Andrii, Vasuki Kilambi, Himabindu, Almekias-Siegl, Efrat, Dikaya, Varvara, Bocobza, Samuel, Shohat, Hagai, Meir, Sagit, Wizler, Guy, Giri, Ashok P, Schuurink, Robert, Weiss, David, Yasuor, Hagai, Kamble, Avinash, Aharoni, Asaph
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't defence gibberellin (GA) growth jasmonate (JA) steroidal glycoalkaloids (SGAs) tomato α-tomatine Alkaloids mehr... Cyclopentanes Gibberellins Oxylipins jasmonic acid 6RI5N05OWW
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520 |a Steroidal glycoalkaloids (SGAs) are protective metabolites constitutively produced by Solanaceae species. Genes and enzymes generating the vast structural diversity of SGAs have been largely identified. Yet, mechanisms of hormone pathways coordinating defence (jasmonate; JA) and growth (gibberellin; GA) controlling SGAs metabolism remain unclear. We used tomato to decipher the hormonal regulation of SGAs metabolism during growth vs defence tradeoff. This was performed by genetic and biochemical characterisation of different JA and GA pathways components, coupled with in vitro experiments to elucidate the crosstalk between these hormone pathways mediating SGAs metabolism. We discovered that reduced active JA results in decreased SGA production, while low levels of GA or its receptor led to elevated SGA accumulation. We showed that MYC1 and MYC2 transcription factors mediate the JA/GA crosstalk by transcriptional activation of SGA biosynthesis and GA catabolism genes. Furthermore, MYC1 and MYC2 transcriptionally regulate the GA signalling suppressor DELLA that by itself interferes in JA-mediated SGA control by modulating MYC activity through protein-protein interaction. Chemical and fungal pathogen treatments reinforced the concept of JA/GA crosstalk during SGA metabolism. These findings revealed the mechanism of JA/GA interplay in SGA biosynthesis to balance the cost of chemical defence with growth 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a defence 
650 4 |a gibberellin (GA) 
650 4 |a growth 
650 4 |a jasmonate (JA) 
650 4 |a steroidal glycoalkaloids (SGAs) 
650 4 |a tomato 
650 4 |a α-tomatine 
650 7 |a Alkaloids  |2 NLM 
650 7 |a Cyclopentanes  |2 NLM 
650 7 |a Gibberellins  |2 NLM 
650 7 |a Oxylipins  |2 NLM 
650 7 |a jasmonic acid  |2 NLM 
650 7 |a 6RI5N05OWW  |2 NLM 
700 1 |a Jozwiak, Adam  |e verfasserin  |4 aut 
700 1 |a Sonawane, Prashant D  |e verfasserin  |4 aut 
700 1 |a Szymanski, Jedrzej  |e verfasserin  |4 aut 
700 1 |a Kazachkova, Yana  |e verfasserin  |4 aut 
700 1 |a Vainer, Andrii  |e verfasserin  |4 aut 
700 1 |a Vasuki Kilambi, Himabindu  |e verfasserin  |4 aut 
700 1 |a Almekias-Siegl, Efrat  |e verfasserin  |4 aut 
700 1 |a Dikaya, Varvara  |e verfasserin  |4 aut 
700 1 |a Bocobza, Samuel  |e verfasserin  |4 aut 
700 1 |a Shohat, Hagai  |e verfasserin  |4 aut 
700 1 |a Meir, Sagit  |e verfasserin  |4 aut 
700 1 |a Wizler, Guy  |e verfasserin  |4 aut 
700 1 |a Giri, Ashok P  |e verfasserin  |4 aut 
700 1 |a Schuurink, Robert  |e verfasserin  |4 aut 
700 1 |a Weiss, David  |e verfasserin  |4 aut 
700 1 |a Yasuor, Hagai  |e verfasserin  |4 aut 
700 1 |a Kamble, Avinash  |e verfasserin  |4 aut 
700 1 |a Aharoni, Asaph  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t The New phytologist  |d 1979  |g 233(2022), 3 vom: 12. Feb., Seite 1220-1237  |w (DE-627)NLM09818248X  |x 1469-8137  |7 nnns 
773 1 8 |g volume:233  |g year:2022  |g number:3  |g day:12  |g month:02  |g pages:1220-1237 
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