Calmodulin-like protein CML24 interacts with CAMTA2 and WRKY46 to regulate ALMT1-dependent Al resistance in Arabidopsis thaliana

Calmodulin-like protein CML24 interacts with CAMTA2 and WRKY46 to regulate ALMT1-dependent Al resistance in Arabidopsis thaliana

© 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 233(2022), 6 vom: 01. März, Seite 2471-2487
1. Verfasser: Zhu, Xue (VerfasserIn)
Weitere Verfasser: Wang, Peng, Bai, Zhimin, Herde, Marco, Ma, Yanqi, Li, Na, Liu, Shuo, Huang, Chao-Feng, Cui, Rongxiu, Ma, Hongyu, Zhang, Meng, Wang, Hui, Wei, Tiandi, Quan, Taiyong, Zhang, Wei, Liu, Chunguang, Zhang, Tao, Yang, Zhong-Bao
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't ALMT1 Arabidopsis roots CML24 aluminium malate exudation Arabidopsis Proteins Calmodulin Malates mehr... Organic Anion Transporters Aluminum CPD4NFA903
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245 1 0 |a Calmodulin-like protein CML24 interacts with CAMTA2 and WRKY46 to regulate ALMT1-dependent Al resistance in Arabidopsis thaliana 
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500 |a CommentIn: New Phytol. 2022 Mar;233(6):2327-2329. - PMID 35175623 
500 |a Citation Status MEDLINE 
520 |a © 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation. 
520 |a ALUMINUM-ACTIVATED MALATE TRANSPORTER1 (ALMT1)-mediated malate exudation from roots is critical for aluminium (Al) resistance in Arabidopsis. Its upstream molecular signalling regulation is not yet well understood. The role of CALMODULIN-LIKE24 (CML24) in Al-inhibited root growth and downstream molecular regulation of ALMT1-meditaed Al resistance was investigated. CML24 confers Al resistance demonstrated by an increased root-growth inhibition of the cml24 loss-of-function mutant under Al stress. This occurs mainly through the regulation of the ALMT1-mediated malate exudation from roots. The mutation and overexpression of CML24 leads to an elevated and reduced Al accumulation in the cell wall of roots, respectively. Al stress induced both transcript and protein abundance of CML24 in root tips, especially in the transition zone. CML24 interacts with CALMODULIN BINDING TRANSCRIPTION ACTIVATOR2 (CAMTA2) and promotes its transcriptional activity in the regulation of ALMT1 expression. This results in an enhanced malate exudation from roots and less root-growth inhibition under Al stress. Both CML24 and CAMTA2 interacted with WRKY46 suppressing the transcriptional repression of ALMT1 by WRKY46. The study provides novel insights into understanding of the upstream molecular signalling of the ALMT1-depdendent Al resistance 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a ALMT1 
650 4 |a Arabidopsis roots 
650 4 |a CML24 
650 4 |a aluminium 
650 4 |a malate exudation 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a Calmodulin  |2 NLM 
650 7 |a Malates  |2 NLM 
650 7 |a Organic Anion Transporters  |2 NLM 
650 7 |a Aluminum  |2 NLM 
650 7 |a CPD4NFA903  |2 NLM 
700 1 |a Wang, Peng  |e verfasserin  |4 aut 
700 1 |a Bai, Zhimin  |e verfasserin  |4 aut 
700 1 |a Herde, Marco  |e verfasserin  |4 aut 
700 1 |a Ma, Yanqi  |e verfasserin  |4 aut 
700 1 |a Li, Na  |e verfasserin  |4 aut 
700 1 |a Liu, Shuo  |e verfasserin  |4 aut 
700 1 |a Huang, Chao-Feng  |e verfasserin  |4 aut 
700 1 |a Cui, Rongxiu  |e verfasserin  |4 aut 
700 1 |a Ma, Hongyu  |e verfasserin  |4 aut 
700 1 |a Zhang, Meng  |e verfasserin  |4 aut 
700 1 |a Wang, Hui  |e verfasserin  |4 aut 
700 1 |a Wei, Tiandi  |e verfasserin  |4 aut 
700 1 |a Quan, Taiyong  |e verfasserin  |4 aut 
700 1 |a Zhang, Wei  |e verfasserin  |4 aut 
700 1 |a Liu, Chunguang  |e verfasserin  |4 aut 
700 1 |a Zhang, Tao  |e verfasserin  |4 aut 
700 1 |a Yang, Zhong-Bao  |e verfasserin  |4 aut 
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