Hierarchical regulation of MYBPA1 by anthocyanin- and proanthocyanidin-related MYB proteins is conserved in Vaccinium species

© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 73(2022), 5 vom: 02. März, Seite 1344-1356
1. Verfasser: Lafferty, Declan J (VerfasserIn)
Weitere Verfasser: Espley, Richard V, Deng, Cecilia H, Günther, Catrin S, Plunkett, Blue, Turner, Janice L, Jaakola, Laura, Karppinen, Katja, Allan, Andrew C, Albert, Nick W
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Vaccinium Anthocyanin MYB berry condensed tannin flavonoid proanthocyanidin transcription factor mehr... Anthocyanins Plant Proteins Proanthocyanidins 18206-61-6
LEADER 01000naa a22002652 4500
001 NLM332049221
003 DE-627
005 20231225214807.0
007 cr uuu---uuuuu
008 231225s2022 xx |||||o 00| ||eng c
024 7 |a 10.1093/jxb/erab460  |2 doi 
028 5 2 |a pubmed24n1106.xml 
035 |a (DE-627)NLM332049221 
035 |a (NLM)34664645 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Lafferty, Declan J  |e verfasserin  |4 aut 
245 1 0 |a Hierarchical regulation of MYBPA1 by anthocyanin- and proanthocyanidin-related MYB proteins is conserved in Vaccinium species 
264 1 |c 2022 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 10.03.2022 
500 |a Date Revised 11.03.2022 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a © The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com. 
520 |a Members of the Vaccinium genus bear fruits rich in anthocyanins, a class of red-purple flavonoid pigments that provide human health benefits, although the localization and concentrations of anthocyanins differ between species: blueberry (V. corymbosum) has white flesh, while bilberry (V. myrtillus) has red flesh. Comparative transcriptomics between blueberry and bilberry revealed that MYBPA1.1 and MYBA1 strongly correlated with the presence of anthocyanins, but were absent or weakly expressed in blueberry flesh. MYBPA1.1 had a biphasic expression profile, correlating with both proanthocyanidin biosynthesis early during fruit development and anthocyanin biosynthesis during berry ripening. MYBPA1.1 was unable to induce anthocyanin or proanthocyanidin accumulation in Nicotiana benthamiana, but activated promoters of flavonoid biosynthesis genes. The MYBPA1.1 promoter is directly activated by MYBA1 and MYBPA2 proteins, which regulate anthocyanins and proanthocyanidins, respectively. Our findings suggest that the lack of VcMYBA1 expression in blueberry flesh results in an absence of VcMYBPA1.1 expression, which are both required for anthocyanin regulation. In contrast, VmMYBA1 is well expressed in bilberry flesh, up-regulating VmMYBPA1.1, allowing coordinated regulation of flavonoid biosynthesis genes and anthocyanin accumulation. The hierarchal model described here for Vaccinium may also occur in a wider group of plants as a means to co-regulate different branches of the flavonoid pathway 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Vaccinium 
650 4 |a Anthocyanin 
650 4 |a MYB 
650 4 |a berry 
650 4 |a condensed tannin 
650 4 |a flavonoid 
650 4 |a proanthocyanidin 
650 4 |a transcription factor 
650 7 |a Anthocyanins  |2 NLM 
650 7 |a Plant Proteins  |2 NLM 
650 7 |a Proanthocyanidins  |2 NLM 
650 7 |a proanthocyanidin  |2 NLM 
650 7 |a 18206-61-6  |2 NLM 
700 1 |a Espley, Richard V  |e verfasserin  |4 aut 
700 1 |a Deng, Cecilia H  |e verfasserin  |4 aut 
700 1 |a Günther, Catrin S  |e verfasserin  |4 aut 
700 1 |a Plunkett, Blue  |e verfasserin  |4 aut 
700 1 |a Turner, Janice L  |e verfasserin  |4 aut 
700 1 |a Jaakola, Laura  |e verfasserin  |4 aut 
700 1 |a Karppinen, Katja  |e verfasserin  |4 aut 
700 1 |a Allan, Andrew C  |e verfasserin  |4 aut 
700 1 |a Albert, Nick W  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Journal of experimental botany  |d 1985  |g 73(2022), 5 vom: 02. März, Seite 1344-1356  |w (DE-627)NLM098182706  |x 1460-2431  |7 nnns 
773 1 8 |g volume:73  |g year:2022  |g number:5  |g day:02  |g month:03  |g pages:1344-1356 
856 4 0 |u http://dx.doi.org/10.1093/jxb/erab460  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 73  |j 2022  |e 5  |b 02  |c 03  |h 1344-1356