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|a Chalfon, Carmit
|e verfasserin
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|a Periarticular histiocytic sarcoma with heart metastasis in a cat
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|c 2021
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|a Text
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|a Date Completed 03.01.2022
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|a Date Revised 31.05.2022
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2021 American Society for Veterinary Clinical Pathology.
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|a A 4-year-old intact female domestic short-haired cat was referred for recommendations about adjuvant medical treatment 1 month after left forelimb amputation due to periarticular histiocytic sarcoma (HS). At presentation, physical abnormalities were limited to enlarged ipsilateral superficial cervical and axillary lymph nodes. Routine blood analysis, abdominal ultrasound, and thoracic radiology were unremarkable. The cat initially received lomustine without any adverse events. Four weeks later, the cat developed severe acute respiratory distress. Results of thoracic radiographs and transthoracic echocardiographic analysis were suggestive of pulmonary and heart metastasis. Due to the cat's poor clinical condition and prognosis, the owner elected euthanasia, and a necropsy was performed. Based on gross pathology, histopathology, and immunohistochemistry, an HS with nodal, renal, pulmonary, and heart (right auricular and right ventricular) metastases was diagnosed. This case represents the first description of HS with a heart metastasis in a cat, providing further insight into the clinical course and metastatic behavior of this rare malignant neoplasm. Clinicians should be aware of this site of metastasis and consider HS in the list of differential diagnoses for secondary heart tumors in cats
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|a Case Reports
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|a cardiac
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|a feline
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|a histiocytes
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|a metastatic disease
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|a neoplasia
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|a Romito, Giovanni
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|a Sabattini, Silvia
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