|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM331750422 |
| 003 |
DE-627 |
| 005 |
20231225214140.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2021 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1002/aah.10142
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1105.xml
|
| 035 |
|
|
|a (DE-627)NLM331750422
|
| 035 |
|
|
|a (NLM)34634147
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Zamana, Roberta Ramblas
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a High Occurrence of Chelonid Alphaherpesvirus 5 (ChHV5) in Green Sea Turtles Chelonia mydas with and without Fibropapillomatosis in Feeding Areas of the São Paulo Coast, Brazil
|
| 264 |
|
1 |
|c 2021
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 02.03.2022
|
| 500 |
|
|
|a Date Revised 02.03.2022
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2021 American Fisheries Society.
|
| 520 |
|
|
|a Chelonid alphaherpesvirus 5 (ChHV5) has been consistently associated with fibropapillomatosis (FP), a neoplastic disease that affects sea turtles globally. The DNA of ChHV5 has been detected in cutaneous and noncutaneous tissues (e.g., lung) of green sea turtles Chelonia mydas with (FP+) and without (FP-) clinical signs of FP, indicating a persistent ChHV5 infection. Previously published and custom primer pairs were used to amplify the fragments of ChHV5 unique long (UL) partial genes (UL30 and UL18) through end-point PCR from cutaneous tumors (n = 31), nontumored skin (n = 49), and lungs (n = 26) from FP+ (n = 31) and FP- (n = 18) green sea turtles. The DNA of ChHV5 was detected in cutaneous tumors (80.6%, 25/31), nontumored skin (74.2%, 23/31 FP+; 27.8%, 5/18 FP-), and lung samples (91.7%, 11/12 FP+; 100%, 14/14 FP-). The high occurrence of ChHV5 observed in lung samples from FP- individuals was unexpected (14/14), providing the first evidence of ChHV5 DNA presence in lungs of individuals without FP. Our results also revealed high ChHV5 occurrence among the tested cohort (93.9%, 46/49) and suggested that a large proportion (83.4%, 15/18) of FP- green sea turtles had subclinical ChHV5 infections. Hence, our findings support the hypothesis that ChHV5 requires one or more possibly environmental or immune-related co-factors to induce FP
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 700 |
1 |
|
|a Gattamorta, Marco Aurélio
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Cruz Ochoa, Pablo Felipe
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Navas-Suárez, Pedro Enrique
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sacristán, Carlos
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rossi, Silmara
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Grisi-Filho, José Henrique Hildebrand
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Silva, Isabela Santos
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Matushima, Eliana Reiko
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of aquatic animal health
|d 1998
|g 33(2021), 4 vom: 01. Dez., Seite 252-263
|w (DE-627)NLM098202006
|x 1548-8667
|7 nnns
|
| 773 |
1 |
8 |
|g volume:33
|g year:2021
|g number:4
|g day:01
|g month:12
|g pages:252-263
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1002/aah.10142
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 33
|j 2021
|e 4
|b 01
|c 12
|h 252-263
|