Probing IgG1 FC-Multimodal Nanoparticle Interactions : A Combined Nuclear Magnetic Resonance and Molecular Dynamics Simulations Approach

In this study, NMR and molecular dynamics simulations were employed to study IgG1 FC binding to multimodal surfaces. Gold nanoparticles functionalized with two multimodal cation-exchange ligands (Capto and Nuvia) were synthesized and employed to carry out solution-phase NMR experiments with the FC....

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 37(2021), 41 vom: 19. Okt., Seite 12188-12203
1. Verfasser: Gudhka, Ronak B (VerfasserIn)
Weitere Verfasser: Vats, Mayank, Bilodeau, Camille L, McCallum, Scott A, McCoy, Mark A, Roush, David J, Snyder, Mark A, Cramer, Steven M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Immunoglobulin G Ligands Gold 7440-57-5