The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis

The chromatin remodelling ATPase BRAHMA interacts with GATA-family transcription factor GNC to regulate flowering time in Arabidopsis

© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.

Bibliographische Detailangaben
Veröffentlicht in:Journal of experimental botany. - 1985. - 73(2022), 3 vom: 27. Jan., Seite 835-847
1. Verfasser: Yang, Jie (VerfasserIn)
Weitere Verfasser: Xu, Yingchao, Wang, Jianhao, Gao, Sujuan, Huang, Yisui, Hung, Fu-Yu, Li, Tao, Li, Qing, Yue, Lin, Wu, Keqiang, Yang, Songguang
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2022
Zugriff auf das übergeordnete Werk:Journal of experimental botany
Schlagworte:Journal Article Research Support, Non-U.S. Gov't BRAHMA (BRM) CARBON METABOLISM INVOLVED) GNC (GATA NITRATE-INDUCIBLE SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) chromatin remodelling flowering time Arabidopsis Proteins mehr... GATA Transcription Factors GNC protein, Arabidopsis Transcription Factors Adenosine Triphosphatases EC 3.6.1.- BRM protein, Arabidopsis EC 3.6.1.3
Beschreibung
Zusammenfassung:© The Author(s) 2021. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
BRAHMA (BRM) is the ATPase of the SWItch/Sucrose Non-Fermentable (SWI/SNF) chromatin remodelling complex, which is indispensable for transcriptional inhibition and activation, associated with vegetative and reproductive development in Arabidopsis thaliana. Here, we show that BRM directly binds to the chromatin of SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1), which integrates multiple flowering signals to regulate floral transition, leading to flowering. In addition, genetic and molecular analysis showed that BRM interacts with GNC (GATA, NITRATE-INDUCIBLE, CARBON METABOLISM INVOLVED), a GATA transcription factor that represses flowering by directly repressing SOC1 expression. Furthermore, BRM is recruited by GNC to directly bind to the chromatin of SOC1. The transcript level of SOC1 is elevated in brm-3, gnc, and brm-3/gnc mutants, which is associated with increased histone H3 lysine 4 tri-methylation (H3K4Me3) but decreased DNA methylation. Taken together, our results indicate that BRM associates with GNC to regulate SOC1 expression and flowering time
Beschreibung:Date Completed 10.03.2022
Date Revised 31.05.2022
published: Print
Citation Status MEDLINE
ISSN:1460-2431
DOI:10.1093/jxb/erab430