Electrophoresis of Liquid-Layer Coated Particles : Impact of Ion Partitioning and Ion Steric Effects

The biomimetic core-shell nanoparticles coated with membranes of various biological cells have attracted significant research interest, because of their extensive applications in targeted drug delivery systems. The cell membrane consists of a lipid bilayer, which can be regarded as a two-dimensional...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 37(2021), 38 vom: 28. Sept., Seite 11316-11329
1. Verfasser: Mahapatra, Paramita (VerfasserIn)
Weitere Verfasser: Ohshima, H, Gopmandal, Partha P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Electrolytes
LEADER 01000naa a22002652 4500
001 NLM330714260
003 DE-627
005 20231225211858.0
007 cr uuu---uuuuu
008 231225s2021 xx |||||o 00| ||eng c
024 7 |a 10.1021/acs.langmuir.1c01875  |2 doi 
028 5 2 |a pubmed24n1102.xml 
035 |a (DE-627)NLM330714260 
035 |a (NLM)34529445 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Mahapatra, Paramita  |e verfasserin  |4 aut 
245 1 0 |a Electrophoresis of Liquid-Layer Coated Particles  |b Impact of Ion Partitioning and Ion Steric Effects 
264 1 |c 2021 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 30.09.2021 
500 |a Date Revised 30.09.2021 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a The biomimetic core-shell nanoparticles coated with membranes of various biological cells have attracted significant research interest, because of their extensive applications in targeted drug delivery systems. The cell membrane consists of a lipid bilayer, which can be regarded as a two-dimensional oriented viscous liquid with low dielectric permittivity, compared to a bulk aqueous medium. Such a liquid layer comprised of cell membrane may bear additional mobile charges, because of the presence of free lipid molecules or charged surfactant molecules, which further results in nonzero charge along the surface of the peripheral layer. In this article, we present an analytical theory for electrophoresis of such cell membrane coated functionalized nanoparticles in the extent of electrolyte solution, considering the combined effects of finite ion size and of ion partitioning. Going beyond the Debye-Huckel approximations, we propose an analytical theory for Donnan potential and electrophoretic mobility. The derived expressions are applicable for moderate to highly charged undertaken core-shell particles when the thickness of the peripheral liquid layer greatly exceeds the electric double layer thickness. The impact of pertinent parameters on the electrophoretic response of such a particle is further discussed 
650 4 |a Journal Article 
650 7 |a Electrolytes  |2 NLM 
700 1 |a Ohshima, H  |e verfasserin  |4 aut 
700 1 |a Gopmandal, Partha P  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 37(2021), 38 vom: 28. Sept., Seite 11316-11329  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:37  |g year:2021  |g number:38  |g day:28  |g month:09  |g pages:11316-11329 
856 4 0 |u http://dx.doi.org/10.1021/acs.langmuir.1c01875  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 37  |j 2021  |e 38  |b 28  |c 09  |h 11316-11329