Skin-Integrated Devices with Soft, Holey Architectures for Wireless Physiological Monitoring, With Applications in the Neonatal Intensive Care Unit

Bibliographische Detailangaben
Veröffentlicht in:	Advanced materials (Deerfield Beach, Fla.). - 1998. - 33(2021), 44 vom: 20. Nov., Seite e2103974
1. Verfasser:	Kwak, Sung Soo (VerfasserIn)
Weitere Verfasser:	Yoo, Seonggwang, Avila, Raudel, Chung, Ha Uk, Jeong, Hyoyoung, Liu, Claire, Vogl, Jamie L, Kim, Joohee, Yoon, Hong-Joon, Park, Yoonseok, Ryu, Hanjun, Lee, Geumbee, Kim, Jihye, Koo, Jahyun, Oh, Yong Suk, Kim, Sungbong, Xu, Shuai, Zhao, Zichen, Xie, Zhaoqian, Huang, Yonggang, Rogers, John A
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2021
Zugriff auf das übergeordnete Werk:	Advanced materials (Deerfield Beach, Fla.)
Schlagworte:	Journal Article electrocardiogram neonates pediatrics physiological monitoring soft electronics wireless wearables

Beschreibung
Zusammenfassung:	© 2021 Wiley-VCH GmbH. Continuous monitoring of vital signs is an essential aspect of operations in neonatal and pediatric intensive care units (NICUs and PICUs), of particular importance to extremely premature and/or critically ill patients. Current approaches require multiple sensors taped to the skin and connected via hard-wired interfaces to external data acquisition electronics. The adhesives can cause iatrogenic injuries to fragile, underdeveloped skin, and the wires can complicate even the most routine tasks in patient care. Here, materials strategies and design concepts are introduced that significantly improve these platforms through the use of optimized materials, open (i.e., "holey") layouts and precurved designs. These schemes 1) reduce the stresses at the skin interface, 2) facilitate release of interfacial moisture from transepidermal water loss, 3) allow visual inspection of the skin for rashes or other forms of irritation, 4) enable triggered reduction of adhesion to reduce the probability for injuries that can result from device removal. A combination of systematic benchtop testing and computational modeling identifies the essential mechanisms and key considerations. Demonstrations on adult volunteers and on a neonate in an operating NICUs illustrate a broad range of capabilities in continuous, clinical-grade monitoring of conventional vital signs, and unconventional indicators of health status
Beschreibung:	Date Completed 24.07.2024 Date Revised 24.07.2024 published: Print-Electronic Citation Status MEDLINE
ISSN:	1521-4095
DOI:	10.1002/adma.202103974