Impact of the COVID-19 pandemic in patients with systemic lupus erythematosus throughout one year

Copyright © 2021 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 231(2021) vom: 07. Okt., Seite 108845
1. Verfasser: Ramirez, Giuseppe A (VerfasserIn)
Weitere Verfasser: Argolini, Lorenza M, Bellocchi, Chiara, Moroni, Luca, Della-Torre, Emanuel, Farina, Nicola, Caporali, Roberto F, Beretta, Lorenzo, Gerosa, Maria, Bozzolo, Enrica P, Dagna, Lorenzo, SMILE, Milan Lupus Consortium
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article COVID-19 Containment Coronavirus Lockdown Prednisone Public health Systemic lupus erythematosus Treatment Vaccination mehr... COVID-19 Vaccines Immunosuppressive Agents
Beschreibung
Zusammenfassung:Copyright © 2021 Elsevier Inc. All rights reserved.
Little is known about the impact of coronavirus disease 2019 (COVID-19) pandemic to the care of patients with systemic lupus erythematosus (SLE) in the long-term. By crossing population data with the results of a web-based survey focused on the timeframes January-April and May-December 2020, we found that among 334/518 responders, 28 had COVID-19 in 2020. Seventeen cases occurred in May-December, in parallel with trends in the general population and loosening of containment policy strength. Age > 40 years (p = 0.026), prednisone escalation (p = 0.008) and infected relatives (p < 0.001) were most significantly associated with COVID-19. Weaker associations were found with asthma, lymphadenopathy and azathioprine or cyclosporine treatment. Only 31% of patients with infected relatives developed COVID-19. Healthcare service disruptions were not associated with rising hospitalisations. Vaccination prospects were generally welcomed. Our data suggest that COVID-19 has a moderate impact on patients with SLE, which might be significantly modulated by public health policies, including vaccination
Beschreibung:Date Completed 13.10.2021
Date Revised 08.09.2024
published: Print-Electronic
Citation Status MEDLINE
ISSN:1521-7035
DOI:10.1016/j.clim.2021.108845