Hair Cell Protection from Ototoxic Drugs
Copyright © 2021 Peng Wu et al.
| Veröffentlicht in: | Neural plasticity. - 1998. - 2021(2021) vom: 10., Seite 4909237 |
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| 1. Verfasser: | |
| Weitere Verfasser: | , , , , |
| Format: | Online-Aufsatz |
| Sprache: | English |
| Veröffentlicht: |
2021
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| Zugriff auf das übergeordnete Werk: | Neural plasticity |
| Schlagworte: | Journal Article Research Support, Non-U.S. Gov't Review Neuroprotective Agents Reactive Oxygen Species |
| Zusammenfassung: | Copyright © 2021 Peng Wu et al. Hearing loss is often caused by death of sensory hair cells (HCs) in the inner ear. HCs are vulnerable to some ototoxic drugs, such as aminoglycosides(AGs) and the cisplatin.The most predominant form of drug-induced cell death is apoptosis. Many efforts have been made to protect HCs from cell death after ototoxic drug exposure. These mechanisms and potential targets of HCs protection will be discussed in this review.And we also propose further investigation in the field of HCs necrosis and regeneration, as well as future clinical utilization |
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| Beschreibung: | Date Completed 20.01.2022 Date Revised 20.01.2022 published: Electronic-eCollection Citation Status MEDLINE |
| ISSN: | 1687-5443 |
| DOI: | 10.1155/2021/4909237 |