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231225s2021 xx |||||o 00| ||eng c |
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|a 10.37616/2212-5043.1258
|2 doi
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|a (NLM)34307015
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|a DE-627
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|a eng
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| 100 |
1 |
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|a Eddarami, Jalila
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Heart Involvement in a Moroccan Population with Spondyloarthritis
|b A Cross-sectional Study
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Revised 13.08.2024
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|a published: Electronic-eCollection
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|a Citation Status PubMed-not-MEDLINE
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|a © 2021 Saudi Heart Association.
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|a OBJECTIVES: The aim of this study was to investigate the prevalence of cardiac manifestations and their predictive factors in Moroccan patients with spondyloarthritis (SpA)
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|a METHODS: We have conducted a cross-sectional study over four months at the Department of Rheumatology in Mohammed VI University Hospital of Oujda, Morocco. All SpA patients fulfilled the 2009 Assessment SpondyloArthritis international Society (ASAS) criteria. Every patient had a cardiac check up including clinical examination, 12-lead electrocardiogram (ECG) and transthoracic echocardiography (TTE). Multiple logistic regression was used to analyze the associated factors with cardiac manifestations
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|a RESULTS: We included 64 men and 30 women with a mean age of 37.32 ± 12.65 years old. The mean disease duration was 10.60 ± 7.61 years. Patients had a mean Ankylosing Spondylitis Disease Activity Score (ASDAS) CRP of 2.25 ± 1.38, a mean Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) of 2.88 ± 2.26 and a mean Bath Ankylosing Spondylitis Functional Index (BASFI) of 33.52 ± 30.49. Traditional cardiovascular risk factors (CVRF) included dyslipidemia in 14.9%, hypertension in 9.6% and type 2 diabetes in 7.4% of the cases. Eight patients (8.5%) smoked and 3 patients (3.2%) used alcohol whereas 20 patients (21.3%) had a history of smoking and 5 patients (6.3%) a history of alcohol. Cardiac manifestations were found in 12 patients (13.3%): 3.3% had aortic regurgitation (AR), 1.1% had aortic dilatation, 1.1% had aortic valve thickening (AVT), 2.2% had mitral thickening, 1.1% had mitral regurgitation (MR), 1.1% had mitral stenosis (MS), 3.3 had pericarditis and 2.2% had complete right bundle branch block (RBBB). In multivariate analysis, cardiac involvement was significantly associated with extra-articular manifestations (OR = 6.05; 95% CI: 1.197-30.607, p = 0.029)
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|a CONCLUSION: Based on these results, cardiac involvement was common and associated with the severity of the disease; hence, early detection of cardiac abnormalities and targeted treatment strategies of SpA and comorbidities are necessary to control the systemic inflammation and improve the excess of cardiovascular mortality in this group of patients
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|a Journal Article
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|a Cardiac manifestations
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| 650 |
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|a Prevalence
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|a Spondyloarthritis
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| 650 |
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|a Valvular heart disease
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| 700 |
1 |
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|a Azzouzi, Hamida
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Ichchou, Linda
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Journal of the Saudi Heart Association
|d 1999
|g 33(2021), 2 vom: 06., Seite 191-197
|w (DE-627)NLM098225227
|x 1016-7315
|7 nnns
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| 773 |
1 |
8 |
|g volume:33
|g year:2021
|g number:2
|g day:06
|g pages:191-197
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|u http://dx.doi.org/10.37616/2212-5043.1258
|3 Volltext
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|d 33
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|h 191-197
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