COVID-19 prevalence and outcomes in patients receiving biologic therapies at an infusion center in New York City

Copyright © 2021 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 230(2021) vom: 01. Sept., Seite 108803
1. Verfasser: Harada, Kaoru (VerfasserIn)
Weitere Verfasser: Ho, Hsi-En, Cunningham-Rundles, Charlotte
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Biologic therapy COVID-19 Immunodeficiencies Immunomodulatory therapy Biological Factors Biomarkers
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520 |a To better understand COVID-19 infection in patients receiving biologic and immunomodulatory therapies, we evaluated prevalence and outcomes for symptomatic cases of COVID-19 at a large therapeutic infusion center in New York City during the height of the pandemic. 2074 patients received treatment with biologic infusions at our center between March and May 2020, and 34 patients developed symptomatic COVID-19 infection, for an overall low rate of 1.64%. The majority of infections and deaths were in a small subset of patients with a primary immunodeficiency. Patients with inflammatory or autoimmune conditions requiring biologic therapies tended to have mild cases. Higher inflammatory responses were observed in patients who died 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Biologic therapy 
650 4 |a COVID-19 
650 4 |a Immunodeficiencies 
650 4 |a Immunomodulatory therapy 
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700 1 |a Ho, Hsi-En  |e verfasserin  |4 aut 
700 1 |a Cunningham-Rundles, Charlotte  |e verfasserin  |4 aut 
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