Plant parasitic cyst nematodes redirect host indole metabolism via NADPH oxidase-mediated ROS to promote infection

Plant parasitic cyst nematodes redirect host indole metabolism via NADPH oxidase-mediated ROS to promote infection

© 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 232(2021), 1 vom: 07. Okt., Seite 318-331
1. Verfasser: Chopra, Divykriti (VerfasserIn)
Weitere Verfasser: Hasan, M Shamim, Matera, Christiane, Chitambo, Oliver, Mendy, Badou, Mahlitz, Sina-Valerie, Naz, Ali Ahmad, Szumski, Shelly, Janakowski, Slawomir, Sobczak, Miroslaw, Mithöfer, Axel, Kyndt, Tina, Grundler, Florian M W, Siddique, Shahid
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. ROS promotes parasitic infection Rboh cyst nematodes plant parasitic nematodes root-knot nematodes syncytium Arabidopsis Proteins mehr... Indoles Reactive Oxygen Species NADPH Oxidases EC 1.6.3.-
LEADER 01000naa a22002652 4500
001 NLM326813535
003 DE-627
005 20231225195416.0
007 cr uuu---uuuuu
008 231225s2021 xx |||||o 00| ||eng c
024 7 |a 10.1111/nph.17559  |2 doi 
028 5 2 |a pubmed24n1089.xml 
035 |a (DE-627)NLM326813535 
035 |a (NLM)34133755 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Chopra, Divykriti  |e verfasserin  |4 aut 
245 1 0 |a Plant parasitic cyst nematodes redirect host indole metabolism via NADPH oxidase-mediated ROS to promote infection 
264 1 |c 2021 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 09.09.2021 
500 |a Date Revised 09.09.2021 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a © 2021 The Authors. New Phytologist © 2021 New Phytologist Foundation. 
520 |a Reactive oxygen species (ROS) generated in response to infections often activate immune responses in eukaryotes including plants. In plants, ROS are primarily produced by plasma membrane-bound NADPH oxidases called respiratory burst oxidase homologue (Rboh). Surprisingly, Rbohs can also promote the infection of plants by certain pathogens, including plant parasitic cyst nematodes. The Arabidopsis genome contains 10 Rboh genes (RbohA-RbohJ). Previously, we showed that cyst nematode infection causes a localised ROS burst in roots, mediated primarily by RbohD and RbohF. We also found that plants deficient in RbohD and RbohF (rbohD/F) exhibit strongly decreased susceptibility to cyst nematodes, suggesting that Rboh-mediated ROS plays a role in promoting infection. However, little information is known of the mechanism by which Rbohs promote cyst nematode infection. Here, using detailed genetic and biochemical analyses, we identified WALLS ARE THIN1 (WAT1), an auxin transporter, as a downstream target of Rboh-mediated ROS during parasitic infections. We found that WAT1 is required to modulate the host's indole metabolism, including indole-3-acetic acid levels, in infected cells and that this reprogramming is necessary for successful establishment of the parasite. In conclusion, this work clarifies a unique mechanism that enables cyst nematodes to use the host's ROS for their own benefit 
650 4 |a Journal Article 
650 4 |a Research Support, Non-U.S. Gov't 
650 4 |a Research Support, U.S. Gov't, Non-P.H.S. 
650 4 |a ROS promotes parasitic infection 
650 4 |a Rboh 
650 4 |a cyst nematodes 
650 4 |a plant parasitic nematodes 
650 4 |a root-knot nematodes 
650 4 |a syncytium 
650 7 |a Arabidopsis Proteins  |2 NLM 
650 7 |a Indoles  |2 NLM 
650 7 |a Reactive Oxygen Species  |2 NLM 
650 7 |a NADPH Oxidases  |2 NLM 
650 7 |a EC 1.6.3.-  |2 NLM 
700 1 |a Hasan, M Shamim  |e verfasserin  |4 aut 
700 1 |a Matera, Christiane  |e verfasserin  |4 aut 
700 1 |a Chitambo, Oliver  |e verfasserin  |4 aut 
700 1 |a Mendy, Badou  |e verfasserin  |4 aut 
700 1 |a Mahlitz, Sina-Valerie  |e verfasserin  |4 aut 
700 1 |a Naz, Ali Ahmad  |e verfasserin  |4 aut 
700 1 |a Szumski, Shelly  |e verfasserin  |4 aut 
700 1 |a Janakowski, Slawomir  |e verfasserin  |4 aut 
700 1 |a Sobczak, Miroslaw  |e verfasserin  |4 aut 
700 1 |a Mithöfer, Axel  |e verfasserin  |4 aut 
700 1 |a Kyndt, Tina  |e verfasserin  |4 aut 
700 1 |a Grundler, Florian M W  |e verfasserin  |4 aut 
700 1 |a Siddique, Shahid  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t The New phytologist  |d 1979  |g 232(2021), 1 vom: 07. Okt., Seite 318-331  |w (DE-627)NLM09818248X  |x 1469-8137  |7 nnns 
773 1 8 |g volume:232  |g year:2021  |g number:1  |g day:07  |g month:10  |g pages:318-331 
856 4 0 |u http://dx.doi.org/10.1111/nph.17559  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 232  |j 2021  |e 1  |b 07  |c 10  |h 318-331