|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM326621997 |
| 003 |
DE-627 |
| 005 |
20231225195005.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2021 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/jfd.13451
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1088.xml
|
| 035 |
|
|
|a (DE-627)NLM326621997
|
| 035 |
|
|
|a (NLM)34114245
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Thanh Dien, Le
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Ozone nanobubble treatments improve survivability of Nile tilapia (Oreochromis niloticus) challenged with a pathogenic multi-drug-resistant Aeromonas hydrophila
|
| 264 |
|
1 |
|c 2021
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 01.11.2021
|
| 500 |
|
|
|a Date Revised 01.11.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2021 John Wiley & Sons Ltd.
|
| 520 |
|
|
|a A rapid increase in multi-drug-resistant (MDR) bacteria in aquaculture highlights the risk of production losses due to diseases and potential public health concerns. Previously, we reported that ozone nanobubbles (NB-O3 ) were effective at reducing concentrations of pathogenic bacteria in water and modulating fish immunity against pathogens; however, multiple treatments with direct NB-O3 exposures caused alterations to the gills of exposed fish. Here, we set up a modified recirculation system (MRS) assembled with an NB-O3 device (MRS-NB-O3 ) to investigate whether MRS-NB-O3 (a) were safe for tilapia (Oreochromis niloticus), (b) were effective at reducing bacterial load in rearing water and (c) improved survivability of Nile tilapia following an immersion challenge with a lethal dose of MDR Aeromonas hydrophila. The results showed no behavioural abnormalities or mortality of Nile tilapia during the 14-day study using the MRS-NB-O3 system. In the immersion challenge, although high bacterial concentration (~2 × 107 CFU/ml) was used, multiple NB-O3 treatments in the first two days reduced the bacteria between 15.9% and 35.6% of bacterial load in water, while bacterial concentration increased from 13.1% to 27.9% in the untreated control. There was slight up-regulation of non-specific immune-related genes in the gills of the fish receiving NB-O3 treatments. Most importantly, this treatment significantly improved survivability of Nile tilapia with relative percentage survival (RPS) of 64.7% - 66.7% in treated fish and surviving fish developed specific antibody against MDR A. hydrophila. In summary, the result suggests that NB-O3 is a promising non-antibiotic approach to control bacterial diseases, including MDR bacteria, and has high potential for application in recirculation aquaculture system (RAS)
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Aeromonas hydrophila
|
| 650 |
|
4 |
|a antimicrobial resistance
|
| 650 |
|
4 |
|a multidrug resistance
|
| 650 |
|
4 |
|a non-antibiotic approach
|
| 650 |
|
4 |
|a ozone nanobubbles
|
| 650 |
|
7 |
|a Ozone
|2 NLM
|
| 650 |
|
7 |
|a 66H7ZZK23N
|2 NLM
|
| 700 |
1 |
|
|a Linh, Nguyen Vu
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sangpo, Pattiya
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Senapin, Saengchan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a St-Hilaire, Sophie
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rodkhum, Channarong
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Dong, Ha Thanh
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 44(2021), 9 vom: 05. Sept., Seite 1435-1447
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
|
| 773 |
1 |
8 |
|g volume:44
|g year:2021
|g number:9
|g day:05
|g month:09
|g pages:1435-1447
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/jfd.13451
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 44
|j 2021
|e 9
|b 05
|c 09
|h 1435-1447
|