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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1155/2021/6615384
|2 doi
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|a eng
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| 100 |
1 |
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|a Chen, Chunli
|e verfasserin
|4 aut
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|a Altered Functional Connectivity in Children with ADHD Revealed by Scalp EEG
|b An ERP Study
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 06.12.2021
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|a Date Revised 02.04.2024
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|a published: Electronic-eCollection
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|a Citation Status MEDLINE
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|a Copyright © 2021 Chunli Chen et al.
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|a Attention deficit hyperactivity disorder (ADHD) is one of the most common neurodevelopmental brain disorders in childhood. Despite extensive researches, the neurobiological mechanism underlying ADHD is still left unveiled. Since the deficit functions, such as attention, have been demonstrated in ADHD, in our present study, based on the oddball P3 task, the corresponding electroencephalogram (EEG) of both healthy controls (HCs) and ADHD children was first collected. And we then not only focused on the event-related potential (ERP) evoked during tasks but also investigated related brain networks. Although an insignificant difference in behavior was found between the HCs and ADHD children, significant electrophysiological differences were found in both ERPs and brain networks. In detail, the dysfunctional attention occurred during the early stage of the designed task; as compared to HCs, the reduced P2 and N2 amplitudes in ADHD children were found, and the atypical information interaction might further underpin such a deficit. On the one hand, when investigating the cortical activity, HCs recruited much stronger brain activity mainly in the temporal and frontal regions, compared to ADHD children; on the other hand, the brain network showed atypical enhanced long-range connectivity between the frontal and occipital lobes but attenuated connectivity among frontal, parietal, and temporal lobes in ADHD children. We hope that the findings in this study may be instructive for the understanding of cognitive processing in children with ADHD
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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1 |
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|a Yang, Huan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Du, Yasong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhai, Guangzhi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xiong, Hesheng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yao, Dezhong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xu, Peng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gong, Jianhua
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yin, Gang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Fali
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Neural plasticity
|d 1998
|g 2021(2021) vom: 31., Seite 6615384
|w (DE-627)NLM098558390
|x 1687-5443
|7 nnas
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| 773 |
1 |
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|g volume:2021
|g year:2021
|g day:31
|g pages:6615384
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|u http://dx.doi.org/10.1155/2021/6615384
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