|
|
|
|
| LEADER |
01000naa a22002652 4500 |
| 001 |
NLM325814902 |
| 003 |
DE-627 |
| 005 |
20231225193237.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2021 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/jfd.13452
|2 doi
|
| 028 |
5 |
2 |
|a pubmed24n1086.xml
|
| 035 |
|
|
|a (DE-627)NLM325814902
|
| 035 |
|
|
|a (NLM)34032302
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Campos-Sánchez, José Carlos
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Effects of subcutaneous injection of λ/κ-carrageenin on the immune and liver antioxidant status of gilthead seabream (Sparus aurata)
|
| 264 |
|
1 |
|c 2021
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 01.11.2021
|
| 500 |
|
|
|a Date Revised 01.11.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © 2021 John Wiley & Sons Ltd.
|
| 520 |
|
|
|a This study investigated the acute inflammatory response induced by subcutaneous injection of carrageenin (1%) or phosphate-buffered saline (control) in gilthead seabream (Sparus aurata). Skin mucus, serum, head kidney (HK) and liver were sampled at 1.5, 3 and 6 hr post-injection (p.i.) to determine the immune and antioxidant status of this fish species. The skin mucus of the carrageenin group showed increased superoxide dismutase and peroxidase activities, lysozyme abundance, bactericidal activity against Vibrio anguillarum and Photobacterium damselae, and total immunoglobulins compared with those of the control group. However, the carrageenin-injected fish sampled at 6 hr p.i. showed decreased protease activity in the skin mucus and peroxidase activity in the HK leucocytes compared with the control. Moreover, the carrageenin injection had no effects on the systemic immune system, but it reduced the liver catalase activities at both 3 and 6 hr in the carrageenin group relative to those in the control group. The expression levels of several proinflammatory and cell marker genes in the HK and liver were also determined. In the HK, the expression levels of interleukin-1β and prostaglandin D synthase 1 were upregulated at 1.5 and 3 hr, respectively, in the carrageenin group compared with those in the control group. Contrarily, the expression of the NADPH oxidase subunit phox40 (an acidophilic granulocyte marker) in the carrageenin group at 6 hr was downregulated compared with that in the control group. These results suggested that subcutaneous injection of κ/λ-carrageenin in gilthead seabream triggered an acute skin inflammation characterized by the rapid recruitment of acidophilic granulocytes and the release of humoral mediators into the skin mucus
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a carrageenin
|
| 650 |
|
4 |
|a granulocyte recruitment
|
| 650 |
|
4 |
|a inflammation
|
| 650 |
|
4 |
|a innate immunity
|
| 650 |
|
4 |
|a marine aquaculture
|
| 650 |
|
4 |
|a teleosts
|
| 650 |
|
7 |
|a Antioxidants
|2 NLM
|
| 650 |
|
7 |
|a Carrageenan
|2 NLM
|
| 650 |
|
7 |
|a 9000-07-1
|2 NLM
|
| 700 |
1 |
|
|a Guardiola, Francisco A
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a García Beltrán, José María
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ceballos-Francisco, Diana
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Esteban, María Ángeles
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 44(2021), 9 vom: 15. Sept., Seite 1449-1462
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
|
| 773 |
1 |
8 |
|g volume:44
|g year:2021
|g number:9
|g day:15
|g month:09
|g pages:1449-1462
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/jfd.13452
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 44
|j 2021
|e 9
|b 15
|c 09
|h 1449-1462
|