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|a 10.1002/adma.202007488
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|a eng
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| 100 |
1 |
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|a Wang, Sheng
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Beyond Photo
|b Xdynamic Therapies in Fighting Cancer
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| 264 |
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|c 2021
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|a Text
|b txt
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|a ƒaComputermedien
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|a Date Completed 24.07.2024
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|a Date Revised 24.07.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2021 Wiley-VCH GmbH.
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|a Reactive oxygen species (ROS)-related therapeutic approaches are developed as a promising modality for cancer treatment because the aberrant increase of intracellular ROS level can cause cell death due to nonspecific oxidation damage to key cellular biomolecules. However, the most widely considered strategy, photodynamic therapy (PDT), suffers from critical limitations such as limited tissue-penetration depth, high oxygen dependence, and phototoxicity. Non-photo-induced ROS generation strategies, which are defined as Xdynamic therapies (X = sono, radio, microwave, chemo, thermo, and electro), show good potential to overcome the drawbacks of PDT. Herein, recent advances in the development of Xdynamic therapies, including the design of systems, the working mechanisms, and examples of cancer therapy application, are introduced. Furthermore, the approaches to enhance treatment efficiency of Xdynamic therapy are highlighted. Finally, the perspectives and challenges of these strategies are also discussed
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|a Journal Article
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|a Review
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|a Xdynamic therapy
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|a cancer
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|a enhanced therapy
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|a nanotechnology
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| 650 |
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|a reactive oxygen species
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| 650 |
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|a Reactive Oxygen Species
|2 NLM
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| 650 |
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|a Photosensitizing Agents
|2 NLM
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| 700 |
1 |
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|a Tian, Rui
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Xu
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Cheng, Guohui
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| 700 |
1 |
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|a Yu, Peng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chang, Jin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Chen, Xiaoyuan
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 33(2021), 25 vom: 13. Juni, Seite e2007488
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|g volume:33
|g year:2021
|g number:25
|g day:13
|g month:06
|g pages:e2007488
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|u http://dx.doi.org/10.1002/adma.202007488
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