Red mark syndrome of trout (Oncorhynchus mykiss; Walbaum, 1792) : Histopathological scoring and correlation with gross lesions

© 2021 The Authors. Journal of Fish Diseases published by John Wiley & Sons Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Journal of fish diseases. - 1998. - 44(2021), 9 vom: 10. Sept., Seite 1325-1336
1. Verfasser: Galeotti, M (VerfasserIn)
Weitere Verfasser: Sarli, G, Sirri, R, Mandrioli, L, Beraldo, P, Bronzatti, P, Giavenni, R, Orioles, M, Magi, G E, Volpatti, D
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Journal of fish diseases
Schlagworte:Journal Article PCNA RMS gross lesions histopathology rainbow trout skin Proliferating Cell Nuclear Antigen
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245 1 0 |a Red mark syndrome of trout (Oncorhynchus mykiss; Walbaum, 1792)  |b Histopathological scoring and correlation with gross lesions 
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520 |a © 2021 The Authors. Journal of Fish Diseases published by John Wiley & Sons Ltd. 
520 |a Red mark syndrome (RMS) is a skin disorder affecting rainbow trout (Oncorhynchus mykiss). The present work aimed to correlate the gross skin lesions affecting 46 fish sampled from farms surveyed for RMS with their microscopic features, identifying histological parameters that may be suggestive of disease progression. Skin lesions were grossly included in one of three categories (types I, II and III) according to the progressive degree of severity. Histological parameters and anti-proliferating cell nuclear antigen (PCNA) tissue immunoreactivity were semi-quantitatively assessed. In the dermis, PCNA-positive lymphocytes, fibroblasts and endothelial cells were indicative of active phlogosis. A significant increase in PCNA-immunoreactive lymphocytes, from gross type I to type III cases, was found only in the hypodermis. The histological parameters significantly associated with the gross lesion severity were progressive loss of the epithelium and scales, recruitment of inflammatory cells in the stratum compactum, loss of architecture of the stratum compactum, perivascular and perineural granulomatous inflammation and increase in lymphocyte infiltration of the muscular layer. In the type II and type III categories, inflammation in the hypodermis and muscle displayed a granulomatous pattern, reinforcing the hypothesis of an immunopathological mechanism. The morphological diagnosis of "deep chronic dermatitis associated to panniculitis and myositis, characterised by lympho-histiocytic and granulomatous reaction" is suggested 
650 4 |a Journal Article 
650 4 |a PCNA 
650 4 |a RMS 
650 4 |a gross lesions 
650 4 |a histopathology 
650 4 |a rainbow trout 
650 4 |a skin 
650 7 |a Proliferating Cell Nuclear Antigen  |2 NLM 
700 1 |a Sarli, G  |e verfasserin  |4 aut 
700 1 |a Sirri, R  |e verfasserin  |4 aut 
700 1 |a Mandrioli, L  |e verfasserin  |4 aut 
700 1 |a Beraldo, P  |e verfasserin  |4 aut 
700 1 |a Bronzatti, P  |e verfasserin  |4 aut 
700 1 |a Giavenni, R  |e verfasserin  |4 aut 
700 1 |a Orioles, M  |e verfasserin  |4 aut 
700 1 |a Magi, G E  |e verfasserin  |4 aut 
700 1 |a Volpatti, D  |e verfasserin  |4 aut 
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773 1 8 |g volume:44  |g year:2021  |g number:9  |g day:10  |g month:09  |g pages:1325-1336 
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