Secure and optimized detection of PNPLA3 rs738409 genotype by an improved PCR-restriction fragment length polymorphism method

The PNPLA3 reference single-nucleotide polymorphism rs738409 has been identified as a predisposing factor for nonalcoholic fatty liver disease. A simple method based on PCR and restriction fragment length polymorphism (RFLP) analysis had been published to detect the nonpathogenic allele PNPLA3 rs738...

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Veröffentlicht in:BioTechniques. - 1991. - 70(2021), 6 vom: 01. Juni, Seite 345-349
1. Verfasser: Enssle, Jörg (VerfasserIn)
Weitere Verfasser: Weylandt, Karsten-Henrich
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't PCR–RFLP PNPLA3 n-3 polyunsaturated fatty acid therapies nonalcoholic fatty liver disease rs738409 Membrane Proteins Lipase EC 3.1.1.3 adiponutrin, human