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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.1c00412
|2 doi
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|a pubmed24n1081.xml
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|a DE-627
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|e rakwb
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|a eng
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| 100 |
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|a Yin, Kunpeng
|e verfasserin
|4 aut
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| 245 |
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|a Lanthanide Metal-Organic Framework-Based Fluorescent Sensor Arrays to Discriminate and Quantify Ingredients of Natural Medicine
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 21.06.2021
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|a Date Revised 21.06.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a The discrimination and quantification of the ingredients from natural medicines are a challenging issue due to their complicated and various structures. Metal-organic frameworks (MOFs) have shown great promise in sensing applications. Here, we report a fluorescent sensor array for rapid identification of some natural compounds using a sensor array composed of four kinds of lanthanide (Eu3+ and Tb3+) fluorescent MOFs (Ln-MOFs), which have diversified fluorescent responses to 26 active/toxic compounds including 12 saponins, 7 flavonoids, 3 stilbenes, and 4 anthraquinones. The fluorescence of the Ln-MOFs after reaction with the compounds was summarized as datasets and processed by principle component analysis (PCA) and hierarchical cluster analysis (HCA) methods. The corresponding responses of the 4 types of compounds are well separated on 2D/3D PCA score plots and HCA dendrograms. We have also tested typical blind samples by concentration-dependent PCA, and an accuracy of 100% was obtained. In addition, the response mechanisms of the Ln-MOFs to the compounds were also studied. Compared with traditional methods using liquid chromatography-mass spectrometry, the developed fluorescent sensor array provides a more efficient and economic strategy to discriminate various active/toxic ingredients in natural medicine
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Fluorescent Dyes
|2 NLM
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|a Lanthanoid Series Elements
|2 NLM
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| 650 |
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|a Metal-Organic Frameworks
|2 NLM
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| 700 |
1 |
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|a Wu, Siqi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zheng, Hao
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gao, Liang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Liu, Jinfeng
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Yang, Chaolong
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Qi, Lian-Wen
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Peng, Juanjuan
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 37(2021), 17 vom: 04. Mai, Seite 5321-5328
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:37
|g year:2021
|g number:17
|g day:04
|g month:05
|g pages:5321-5328
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|u http://dx.doi.org/10.1021/acs.langmuir.1c00412
|3 Volltext
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