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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202006651
|2 doi
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|a pubmed24n1481.xml
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|a eng
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|a Khojah, Reem
|e verfasserin
|4 aut
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|a Single-Domain Multiferroic Array-Addressable Terfenol-D (SMArT) Micromagnets for Programmable Single-Cell Capture and Release
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 24.07.2024
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|a Date Revised 24.07.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2021 Wiley-VCH GmbH.
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|a Programming magnetic fields with microscale control can enable automation at the scale of single cells ≈10 µm. Most magnetic materials provide a consistent magnetic field over time but the direction or field strength at the microscale is not easily modulated. However, magnetostrictive materials, when coupled with ferroelectric material (i.e., strain-mediated multiferroics), can undergo magnetization reorientation due to voltage-induced strain, promising refined control of magnetization at the micrometer-scale. This work demonstrates the largest single-domain microstructures (20 µm) of Terfenol-D (Tb0.3 Dy0.7 Fe1.92 ), a material that has the highest magnetostrictive strain of any known soft magnetoelastic material. These Terfenol-D microstructures enable controlled localization of magnetic beads with sub-micrometer precision. Magnetically labeled cells are captured by the field gradients generated from the single-domain microstructures without an external magnetic field. The magnetic state on these microstructures is switched through voltage-induced strain, as a result of the strain-mediated converse magnetoelectric effect, to release individual cells using a multiferroic approach. These electronically addressable micromagnets pave the way for parallelized multiferroics-based single-cell sorting under digital control for biotechnology applications
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|a Journal Article
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|a Terfenol-D
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|a magnetoelastic materials
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|a multiferroics
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|a single-cell separation
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|a single-domain materials
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|a Xiao, Zhuyun
|e verfasserin
|4 aut
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|a Panduranga, Mohanchandra K
|e verfasserin
|4 aut
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|a Bogumil, Michael
|e verfasserin
|4 aut
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|a Wang, Yilian
|e verfasserin
|4 aut
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|a Goiriena-Goikoetxea, Maite
|e verfasserin
|4 aut
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| 700 |
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|a Chopdekar, Rajesh V
|e verfasserin
|4 aut
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|a Bokor, Jeffrey
|e verfasserin
|4 aut
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|a Carman, Gregory P
|e verfasserin
|4 aut
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|a Candler, Rob N
|e verfasserin
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|a Di Carlo, Dino
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 33(2021), 20 vom: 08. Mai, Seite e2006651
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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|g volume:33
|g year:2021
|g number:20
|g day:08
|g month:05
|g pages:e2006651
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|u http://dx.doi.org/10.1002/adma.202006651
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