|
|
|
|
| LEADER |
01000caa a22002652c 4500 |
| 001 |
NLM323312179 |
| 003 |
DE-627 |
| 005 |
20250301073742.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2021 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1016/j.plantsci.2021.110863
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n1077.xml
|
| 035 |
|
|
|a (DE-627)NLM323312179
|
| 035 |
|
|
|a (NLM)33775368
|
| 035 |
|
|
|a (PII)S0168-9452(21)00052-2
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Casatejada-Anchel, Rubén
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Phosphoglycerate dehydrogenase genes differentially affect Arabidopsis metabolism and development
|
| 264 |
|
1 |
|c 2021
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 14.04.2021
|
| 500 |
|
|
|a Date Revised 14.04.2021
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Copyright © 2021 Elsevier B.V. All rights reserved.
|
| 520 |
|
|
|a Unlike animals, plants possess diverse L-serine (Ser) biosynthetic pathways. One of them, the Phosphorylated Pathway of Serine Biosynthesis (PPSB) has been recently described as essential for embryo, pollen and root development, and required for ammonium and sulfur assimilation. The first and rate limiting step of PPSB is the reaction catalyzed by the enzyme phosphoglycerate dehydrogenase (PGDH). In Arabidopsis, the PGDH family consists of three genes, PGDH1, PGDH2 and PGDH3. PGDH1 is characterized as being the essential gene of the family. However, the biological significance of PGDH2 and PGDH3 remains unknown. In this manuscript, we have functionally characterized PGDH2 and PGDH3. Phenotypic, metabolomic and gene expression analysis in PGDH single, double and triple mutants indicate that both PGDH2 and PGDH3 are functional, affecting plant metabolism and development. PGDH2 has a stronger effect on plant growth than PGDH3, having a partial redundant role with PGDH1. PGDH3, however, could have additional functions in photosynthetic cells unrelated to Ser biosynthesis
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a PGDH
|
| 650 |
|
4 |
|a PSP
|
| 650 |
|
4 |
|a Phosphoglycerate dehydrogenase
|
| 650 |
|
4 |
|a Phosphorylated pathway of serine biosynthesis
|
| 650 |
|
4 |
|a Phosphoserine phosphatase
|
| 650 |
|
4 |
|a Serine
|
| 650 |
|
7 |
|a Serine
|2 NLM
|
| 650 |
|
7 |
|a 452VLY9402
|2 NLM
|
| 650 |
|
7 |
|a Phosphoglycerate Dehydrogenase
|2 NLM
|
| 650 |
|
7 |
|a EC 1.1.1.95
|2 NLM
|
| 700 |
1 |
|
|a Muñoz-Bertomeu, Jesús
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Rosa-Téllez, Sara
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Anoman, Armand D
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Nebauer, Sergio G
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Torres-Moncho, Alejandro
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Fernie, Alisdair R
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Ros, Roc
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Plant science : an international journal of experimental plant biology
|d 1985
|g 306(2021) vom: 20. Mai, Seite 110863
|w (DE-627)NLM098174193
|x 1873-2259
|7 nnas
|
| 773 |
1 |
8 |
|g volume:306
|g year:2021
|g day:20
|g month:05
|g pages:110863
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1016/j.plantsci.2021.110863
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 306
|j 2021
|b 20
|c 05
|h 110863
|