A Hippocampus-Inspired Dual-Gated Organic Artificial Synapse for Simultaneous Sensing of a Neurotransmitter and Light

© 2021 Wiley-VCH GmbH.

Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Deerfield Beach, Fla.). - 1998. - 33(2021), 17 vom: 13. Apr., Seite e2100119
1. Verfasser: Lee, Hae Rang (VerfasserIn)
Weitere Verfasser: Lee, Doyoung, Oh, Joon Hak
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Advanced materials (Deerfield Beach, Fla.)
Schlagworte:Journal Article artificial synapses dopamine detection dual-gate transistors hippocampal synapses light detection Neurotransmitter Agents Dopamine VTD58H1Z2X Boronic Acids Polymers
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520 |a Organic neuromorphic devices and sensors that mimic the functions of chemical synapses and sensory perception in humans have received much attention for next-generation computing and integrated logic circuits. Despite recent advances, organic artificial synapses capable of detecting both neurotransmitters in liquid environments and light are not reported. Herein, inspired by hippocampal synapses, a dual-gate organic synaptic transistor platform with a photoconductive polymer semiconductor, a ferroelectric insulator of P(VDF-TrFE), and an extended-gate electrode functionalized with boronic acid is developed to simultaneously detect the neurotransmitter dopamine and light. The developed synaptic transistor enables memory consolidation upon repetitive exposure to dopamine and polychromatic light, exhibiting effectively modulated postsynaptic currents. This proof-of-concept hippocampal-synapse-mimetic organic neuromorphic system combining a chemical sensor and a photosensor opens new possibilities for developing low-power organic artificial synaptic multisensors and light-induced memory consolidative artificial synapses, and can also contribute to the development of human-machine interfaces 
650 4 |a Journal Article 
650 4 |a artificial synapses 
650 4 |a dopamine detection 
650 4 |a dual-gate transistors 
650 4 |a hippocampal synapses 
650 4 |a light detection 
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650 7 |a Dopamine  |2 NLM 
650 7 |a VTD58H1Z2X  |2 NLM 
650 7 |a Boronic Acids  |2 NLM 
650 7 |a Polymers  |2 NLM 
700 1 |a Lee, Doyoung  |e verfasserin  |4 aut 
700 1 |a Oh, Joon Hak  |e verfasserin  |4 aut 
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