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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202008540
|2 doi
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|a pubmed24n1481.xml
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|e rakwb
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|a eng
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| 100 |
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|a He, Ting
|e verfasserin
|4 aut
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|a Manganese-Dioxide-Coating-Instructed Plasmonic Modulation of Gold Nanorods for Activatable Duplex-Imaging-Guided NIR-II Photothermal-Chemodynamic Therapy
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 24.07.2024
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|a Date Revised 24.07.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2021 Wiley-VCH GmbH.
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|a Nanotheranostic agents of gold nanomaterials in the second near-infrared (NIR-II) window have attracted significant attention in cancer management, owing to the reduced background signal and deeper penetration depth in tissues. However, it is still challenging to modulate the localized surface plasmon resonance (LSPR) of gold nanomaterials from the first near-infrared (NIR-I) to NIR-II region. Herein, a plasmonic modulation strategy of gold nanorods (GNRs) through manganese dioxide coating is developed for NIR-II photoacoustic/magnetic resonance (MR) duplex-imaging-guided NIR-II photothermal chemodynamic therapy. GNRs are coated with silica dioxide (SiO2 ) and then covered with magnesium dioxide (MnO2 ) to obtain the final product of GNRSiO2 @MnO2 (denoted as GSM). The LSPR peak of GNRs could be tuned by adjusting the thickness of the MnO2 layer. Theoretical simulations reveal that this plasmonic modulation is mainly due to the change of refraction index around the GNRs after coating with the MnO2 layer. Additionally, the MnO2 layer is demonstrated to degrade into Mn2+ ions in response to peroxide and acidic protons in the tumor microenvironment, which allows for MR imaging and chemodynamic therapy. This plasmonic modulation strategy can be adapted to other metal nanomaterials and the construction of a new class of NIR-II nanotheranostics
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|a Journal Article
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|a NIR-II
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|a duplex imaging
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|a gold nanorods
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|a manganese dioxide
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|a photothermal-chemodynamic therapy
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|a Gold
|2 NLM
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|a 7440-57-5
|2 NLM
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|a Manganese Compounds
|2 NLM
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|a Oxides
|2 NLM
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|a manganese dioxide
|2 NLM
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|a TF219GU161
|2 NLM
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|a Silicon Dioxide
|2 NLM
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|a 7631-86-9
|2 NLM
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| 700 |
1 |
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|a Jiang, Chao
|e verfasserin
|4 aut
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| 700 |
1 |
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|a He, Jin
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Yifan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a He, Gang
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wu, Jiayingzi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lin, Jing
|e verfasserin
|4 aut
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| 700 |
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|a Zhou, Xin
|e verfasserin
|4 aut
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|a Huang, Peng
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 33(2021), 13 vom: 01. Apr., Seite e2008540
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnns
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| 773 |
1 |
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|g volume:33
|g year:2021
|g number:13
|g day:01
|g month:04
|g pages:e2008540
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|u http://dx.doi.org/10.1002/adma.202008540
|3 Volltext
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