Partitioning of Seven Different Classes of Antibiotics into LPS Monolayers Supports Three Different Permeation Mechanisms through the Outer Bacterial Membrane
The outer membrane (OM) of Gram-negative (G-) bacteria presents a barrier for many classes of antibacterial agents. Lipopolysaccharide (LPS), present in the outer leaflet of the OM, is stabilized by divalent cations and is considered to be the major impediment for antibacterial agent permeation. How...
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Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 37(2021), 4 vom: 02. Feb., Seite 1372-1385
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| 1. Verfasser: |
Cetuk, Hannah
(VerfasserIn) |
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| Weitere Verfasser: |
Anishkin, Andriy,
Scott, Alison J,
Rempe, Susan B,
Ernst, Robert K,
Sukharev, Sergei |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2021
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, U.S. Gov't, Non-P.H.S.
Anti-Bacterial Agents
Lipopolysaccharides
Porins |
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