Antifungal Activity and Biological Characteristics of the Novel Fungicide Quinofumelin Against Sclerotinia sclerotiorum

Sclerotinia sclerotiorum is a devastating plant pathogen with a broad host range and worldwide distribution. The application of chemical fungicides is a primary strategy for controlling this pathogen. However, under the high selective pressure of chemical fungicides, fungicide resistance has emerged...

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Veröffentlicht in:Plant disease. - 1997. - 105(2021), 9 vom: 06. Sept., Seite 2567-2574
1. Verfasser: Tao, Xian (VerfasserIn)
Weitere Verfasser: Zhao, Huahua, Xu, Haorong, Li, Zhongke, Wang, Jianxin, Song, Xiushi, Zhou, Mingguo, Duan, Yabing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Plant disease
Schlagworte:Journal Article Sclerotinia sclerotiorum antifungal activity biological characteristics quinofumelin Antifungal Agents Fungicides, Industrial
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520 |a Sclerotinia sclerotiorum is a devastating plant pathogen with a broad host range and worldwide distribution. The application of chemical fungicides is a primary strategy for controlling this pathogen. However, under the high selective pressure of chemical fungicides, fungicide resistance has emerged and gradually increased, resulting in the failure to control S. sclerotiorum in the field. Quinofumelin is a novel quinoline fungicide, but its antifungal activities against plant pathogens have been rarely reported. Here, we determined the antifungal activity of quinofumelin against S. sclerotiorum in vitro and in planta. The median effect concentration (EC50) values ranged from 0.0004 to 0.0059 µg ml-1 with a mean EC50 of 0.0017 ± 0.0009 µg ml-1 and were normally distributed (P = 0.402). In addition, no cross resistance was observed between quinofumelin and other fungicides, dimethachlone, boscalid, or carbendazim, which are commonly used to manage S. sclerotiorum. Quinofumelin did not affect glycerol and oxalic acid production of either carbendazim-sensitive or -resistant isolates. Moreover, quinofumelin exhibited excellent protective, curative, and translaminar activity against S. sclerotiorum on oilseed rape leaves. Protective activity was higher than curative activity. Interestingly, quinofumelin inhibited the formation of the infection cushion in S. sclerotiorum, which may contribute to the control efficacy of quinofumelin against S. sclerotiorum in the field. Our findings indicate that quinofumelin has excellent control efficacy against S. sclerotiorum in vitro and in planta as compared with extensively used fungicides and could be used to manage carbendazim- and dimethachlone-resistance in S. sclerotiorum in the field 
650 4 |a Journal Article 
650 4 |a Sclerotinia sclerotiorum 
650 4 |a antifungal activity 
650 4 |a biological characteristics 
650 4 |a quinofumelin 
650 7 |a Antifungal Agents  |2 NLM 
650 7 |a Fungicides, Industrial  |2 NLM 
700 1 |a Zhao, Huahua  |e verfasserin  |4 aut 
700 1 |a Xu, Haorong  |e verfasserin  |4 aut 
700 1 |a Li, Zhongke  |e verfasserin  |4 aut 
700 1 |a Wang, Jianxin  |e verfasserin  |4 aut 
700 1 |a Song, Xiushi  |e verfasserin  |4 aut 
700 1 |a Zhou, Mingguo  |e verfasserin  |4 aut 
700 1 |a Duan, Yabing  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Plant disease  |d 1997  |g 105(2021), 9 vom: 06. Sept., Seite 2567-2574  |w (DE-627)NLM098181742  |x 0191-2917  |7 nnns 
773 1 8 |g volume:105  |g year:2021  |g number:9  |g day:06  |g month:09  |g pages:2567-2574 
856 4 0 |u http://dx.doi.org/10.1094/PDIS-08-20-1821-RE  |3 Volltext 
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