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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1111/vcp.12926
|2 doi
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|a pubmed24n1064.xml
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|a (DE-627)NLM319328279
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|a (NLM)33368568
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Buriko, Yekaterina
|e verfasserin
|4 aut
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|a Establishment of normal reference intervals in dogs using a viscoelastic point-of-care coagulation monitor and its comparison with thromboelastography
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|c 2020
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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|a Date Completed 17.09.2021
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|a Date Revised 17.09.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2020 American Society for Veterinary Clinical Pathology.
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|a BACKGROUND: Viscoelastic coagulation devices are a useful adjunct to the evaluation of hemostasis in veterinary patients. VCM Vet is a point-of-care device that is simple in operation and could be used to diagnose and trend hemostatic abnormalities in sick patients. VCM Vet does not use activators
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|a OBJECTIVES: We aimed to establish reference intervals (RIs) for VCM Vet in a healthy adult canine population and concurrently perform thromboelastographic (TEG) analysis on these samples with and without tissue factor (TF) activation for RI comparisons
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|a METHODS: Duplicate VCM Vet tests were performed immediately upon sample collection. Two concurrent TEG tests were performed on the remaining blood, one citrated, untreated (CU), and one activated with TF at a 1:3600 dilution
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|a RESULTS: Fifty-two dogs were enrolled in the study. The following RIs were generated for VCM Vet machine 1 and 2, respectively: clot time (CT) (seconds) 163-480 and 172-457; clot formation time (CFT) (seconds) 104-288 and 94-252, α-angle (degrees) 41-65 and 44-66, and maximum clot firmness (MCF) (no units) 27-43 and 30-46. Moderate to good correlations were observed between the two machines with Lin's concordance correlation coefficients of 0.51-0.9 and a P < 0.002. TEG RIs were similar to previously reported values
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|a CONCLUSIONS: VCM Vet RIs were generated. Each VCM Vet device should have a unique RI established due to inter-device variability. Direct correlations of VCM Vet values with TEG parameters were not performed due to the narrow range of the normal values and the need to evaluate patients with a wide range of hemostatic abnormalities
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|a Journal Article
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|a analyzer
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|a clotting
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|a device
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|a hemostasis
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|a Drobatz, Kenneth
|e verfasserin
|4 aut
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|a Silverstein, Deborah C
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 49(2020), 4 vom: 01. Dez., Seite 567-573
|w (DE-627)NLM098159984
|x 1939-165X
|7 nnns
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| 773 |
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|g volume:49
|g year:2020
|g number:4
|g day:01
|g month:12
|g pages:567-573
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|u http://dx.doi.org/10.1111/vcp.12926
|3 Volltext
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