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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1021/acs.langmuir.0c02894
|2 doi
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|a pubmed24n1063.xml
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|e rakwb
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|a eng
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| 100 |
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|a El Hamoui, Omar
|e verfasserin
|4 aut
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| 245 |
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|a Self-Assembly of Nucleoside-Derived Low-Molecular-Weight Gelators
|b A Thermodynamics and Kinetics Study on Different Length Scales
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 21.01.2021
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|a Date Revised 21.01.2021
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|a published: Print-Electronic
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|a Citation Status PubMed-not-MEDLINE
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|a Biocompatible materials are of paramount importance in numerous fields. Unlike chemically bridge polymer-based hydrogels, low-molecular-weight gelators can form a reversible hydrogel as their structures rely on noncovalent interaction. Although many applications with this type of hydrogel can be envisioned, we still lack their understanding due to the complexity of their self-assembly process and the difficulty in predicting their behaviors (transition temperature, gelation kinetics, the impact of solvent, etc.). In this study, we extend the investigations of a series of nucleoside-derived gelators, which only differ by subtle chemical modifications. Using a multitechnique approach, we determined their thermodynamic and kinetic features on various scale (molecular to macro) in different conditions. Monitored at the supramolecular level by circular dichroism as well as macroscopic scales by rheology and turbidimetry, we found out that the sol-gel and gel-sol transitions are greatly dependent on the concentration and on the mechanisms that are probed. Self-assembly kinetics depends on hydrogel molecules and is modulated by temperature and solvent. This fundamental study provides insight on the impact of some parameters on the gelation process, such as concentration, cooling rate, and the nature of the solvent
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Gaudin, Karen
|e verfasserin
|4 aut
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|a Battu, Serge
|e verfasserin
|4 aut
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| 700 |
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|a Barthélémy, Philippe
|e verfasserin
|4 aut
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|a Lespes, Gaëtane
|e verfasserin
|4 aut
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|a Alies, Bruno
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1992
|g 37(2021), 1 vom: 12. Jan., Seite 297-310
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnns
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| 773 |
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|g volume:37
|g year:2021
|g number:1
|g day:12
|g month:01
|g pages:297-310
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|u http://dx.doi.org/10.1021/acs.langmuir.0c02894
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