Discrete Left Ventricle Outflow Tract Obstruction in Children Incidence and Predictors of Recurrence. A Multi-Center Study

Discrete Left Ventricle Outflow Tract Obstruction in Children : Incidence and Predictors of Recurrence. A Multi-Center Study

© 2020 Saudi Heart Association.

Bibliographische Detailangaben
Veröffentlicht in:Journal of the Saudi Heart Association. - 1999. - 32(2020), 3 vom: 01., Seite 358-364
1. Verfasser: Alqurashi, Gadah M (VerfasserIn)
Weitere Verfasser: Almohanna, Rema S, Ayoub, Kamal M K, Alkhuraiji, Arwa A, Almasoud, Najla A, Alsubaie, Amjad R, Althubaiti, Alaa M, Al Sehly, Abdullah A
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Journal of the Saudi Heart Association
Schlagworte:Journal Article Discrete subaortic stenosis Membrane resection Subaortic stenosis Subaortic stenosis recurrence
Beschreibung
Zusammenfassung:© 2020 Saudi Heart Association.
OBJECTIVES: The purpose of this study is to measure the incidence of recurrence of discrete subaortic stenosis (DSS) after primary resection in two major cardiac centers in Saudi Arabia and to identify risk factors associated with recurrence
METHODS: Data on 234 patients who were diagnosed with DSS and underwent surgical resection between 1999 and 2018 were retrospectively reviewed. Patient demographics as well as echocardiographic, surgical, and pathological data were compared between patients with recurrence and non-recurrence
RESULTS: The overall recurrence incidence after primary resection was 44.87% (N = 105). Most patients were male (59%). The median age at the 1st operation was 60 months (range 3 months to 133 months). The presence of aortic stenosis at the time of diagnosis was significantly associated with recurrence (p-value = 0.002). The overall median peak gradient in which the primary resection was indicated is 60 mmHg (range 11 to 152 mmHg). The median peak gradient pre-operation and post-operation were significantly higher for the recurrence group (p-value=0.018 and p<0.001, respectively). We used univariate and multivariate analysis and controlled for the follow-up time, but there were no significant independent predictors of recurrence
CONCLUSION: The recurrence rate of DSS after the primary resection is relatively high in this study. Further prospective studies are needed to draw a definite conclusion on risk factors for recurrence after primary resection
Beschreibung:Date Revised 18.04.2022
published: Electronic-eCollection
Citation Status PubMed-not-MEDLINE
ISSN:1016-7315
DOI:10.37616/2212-5043.1045