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|a 10.1093/jxb/eraa463
|2 doi
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|a DE-627
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|a eng
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|a Rönspies, Michelle
|e verfasserin
|4 aut
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|a CRISPR/Cas-mediated chromosome engineering
|b opening up a new avenue for plant breeding
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 13.05.2021
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|a Date Revised 13.05.2021
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|a published: Print
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|a Citation Status MEDLINE
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|a © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
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|a The advent of powerful site-specific nucleases, particularly the clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein (Cas) system, which enables precise genome manipulation, has revolutionized plant breeding. Until recently, the main focus of researchers has been to simply knock-in or knock-out single genes, or to induce single base changes, but constant improvements of this technology have enabled more ambitious applications that aim to improve plant productivity or other desirable traits. One long-standing aim has been the induction of targeted chromosomal rearrangements (crossovers, inversions, or translocations). The feasibility of this technique has the potential to transform plant breeding, because natural rearrangements, like inversions, for example, typically present obstacles to the breeding process. In this way, genetic linkages between traits could be altered to combine or separate favorable and deleterious genes, respectively. In this review, we discuss recent breakthroughs in the field of chromosome engineering in plants and their potential applications in the field of plant breeding. In the future, these approaches might be applicable in shaping plant chromosomes in a directed manner, based on plant breeding needs
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Review
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|a Arabidopsis
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|a CRISPR/Cas9
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| 650 |
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|a chromosomal rearrangements
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|a gene editing
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| 650 |
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|a genome engineering
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| 650 |
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|a inversion
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|a plant breeding
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| 650 |
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|a translocation
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|a Schindele, Patrick
|e verfasserin
|4 aut
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|a Puchta, Holger
|e verfasserin
|4 aut
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|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 72(2021), 2 vom: 02. Feb., Seite 177-183
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnas
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| 773 |
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|g volume:72
|g year:2021
|g number:2
|g day:02
|g month:02
|g pages:177-183
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|u http://dx.doi.org/10.1093/jxb/eraa463
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