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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202003883
|2 doi
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|a eng
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| 100 |
1 |
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|a Alsharabasy, Amir M
|e verfasserin
|4 aut
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| 245 |
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|a Recent Advances in the Design and Sensing Applications of Hemin/Coordination Polymer-Based Nanocomposites
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|c 2021
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|a Text
|b txt
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 24.07.2024
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|a Date Revised 24.07.2024
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2020 The Authors. Published by Wiley-VCH GmbH.
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|a The fabrication of biomimetic catalysts as substituents for enzymes is of critical interest in the field due to the problems associated with the extraction, purification, and storage of enzymes in sensing applications. Of these mimetics, hemin/coordination polymer-based nanocomposites, mainly hemin/metal-organic frameworks (MOF), have been developed for various biosensing applications because of the unique properties of each component, while trying to mimic the normal biological functions of heme within the protein milieu of enzymes. This critical review first discusses the different catalytic functions of heme in the body in the form of enzyme/protein structures. The properties of hemin dimerization are then elucidated with the supposed models of hemin oxidation. After that, the progress in the fabrication of hemin/MOF nanocomposites for the sensing of diverse biological molecules is discussed. Finally, the challenges in developing this type of composites are examined as well as possible proposals for future directions to enhance the sensing performance in this field further
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|a Journal Article
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|a Review
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|a biosensing
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|a coordination polymers
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4 |
|a hemin
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|a hemin aggregation
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|a metal-organic frameworks
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| 650 |
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|a Hemin
|2 NLM
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|a 743LRP9S7N
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|a Polymers
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|a Metal-Organic Frameworks
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| 700 |
1 |
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|a Pandit, Abhay
|e verfasserin
|4 aut
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1 |
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|a Farràs, Pau
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 33(2021), 2 vom: 15. Jan., Seite e2003883
|w (DE-627)NLM098206397
|x 1521-4095
|7 nnas
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|g volume:33
|g year:2021
|g number:2
|g day:15
|g month:01
|g pages:e2003883
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|u http://dx.doi.org/10.1002/adma.202003883
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