Recombinant viral proteins delivered orally through inactivated bacterial cells induce protection in Macrobrachium rosenbergii (de Man) against White Tail Disease

© 2020 John Wiley & Sons Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Journal of fish diseases. - 1998. - 44(2021), 5 vom: 01. Mai, Seite 601-612
1. Verfasser: NaveenKumar, Singaiah (VerfasserIn)
Weitere Verfasser: Rai, Praveen, Karunasagar, Indrani, Karunasagar, Iddya
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:Journal of fish diseases
Schlagworte:Journal Article oral administration protection recombinant protein white tail disease Capsid Proteins Recombinant Proteins Vaccines, Inactivated Viral Vaccines
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520 |a White tail disease (WTD) is a disease of Macrobrachium rosenbergii caused by Macrobrachium rosenbergii nodavirus (MrNV) and extra small virus (XSV) with the potential to devastate the aquaculture industry. The present study aimed to explore the possible protection of M. rosenbergii against the disease by oral administration of bacterially expressed recombinant capsid proteins of MrNV and XSV. Juvenile M. rosenbergii were fed with the feed coated with inactivated bacteria encapsulated expressed recombinant viral proteins either individually or in combination for 7 days. Challenge studies using WTD causing agents were carried out after 3 (group I), 10 (group II) and 20 (group III) days post-feeding of viral proteins. Recombinant capsid protein of MrNV showed better protection when compared to other treatments with relative per cent survival of 62.5% (group I), 57.9% (group II) and 39.5% (group III). Treatment controls of groups I, II and III showed 100%, 95% and 95% mortality, respectively. The study demonstrates that oral administration of recombinant capsid proteins of MrNV and XSV provides effective protection against WTD in freshwater prawn 
650 4 |a Journal Article 
650 4 |a oral administration 
650 4 |a protection 
650 4 |a recombinant protein 
650 4 |a white tail disease 
650 7 |a Capsid Proteins  |2 NLM 
650 7 |a Recombinant Proteins  |2 NLM 
650 7 |a Vaccines, Inactivated  |2 NLM 
650 7 |a Viral Vaccines  |2 NLM 
700 1 |a Rai, Praveen  |e verfasserin  |4 aut 
700 1 |a Karunasagar, Indrani  |e verfasserin  |4 aut 
700 1 |a Karunasagar, Iddya  |e verfasserin  |4 aut 
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