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231225s2021 xx |||||o 00| ||eng c |
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|a 10.1007/s10646-020-02308-y
|2 doi
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|a pubmed25n1058.xml
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|a eng
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|a Yang, Li
|e verfasserin
|4 aut
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|a Estimating the synergistic and antagonistic effects of dual antibiotics on plants through root elongation test
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|c 2021
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 13.09.2021
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|a Date Revised 13.09.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2020. Springer Science+Business Media, LLC, part of Springer Nature.
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|a Antibiotics are recently recognized as a group of emerging environmental contaminants that are frequently detected in various environmental matrixes. Relative root elongation (RRE) test is a rapid and effective strategy to evaluate the water/soil quality and the toxic effects of environmental contaminants on plants. In the present study, we examine the toxicity effect of ciprofloxacin (CIP), norfloxacin (NOR), and tetracycline (TET) to pakchoi individually and in combinations. Both independent action (IA) and concentration addition (CA) models are used for toxicity assessment. Results showed that the EC50 values of CIP, NOR, and TET are 193.59, 60.81, and 40.37 μM, respectively. Combinations of TET + CIP and TET + NOR caused more inhibitory effects on root elongation than those of CIP + NOR. Toxic Unit (TU) and Synergistic Ratio (SR) analysis showed that the relatively lower (higher) EC values are observed in the combinations with lower (higher) antibiotic concentrations, suggesting an effect of low-dose synergism and high-dose antagonism. The reliability of the simulation results from IA and CA models to predict that combined toxicity is highly dependent upon the results from the analysis of TU or SR
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|a Journal Article
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|a Antibiotic
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|a CA/IA model
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|a Effective concentration
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|a Root elongation
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|a TU/SR method
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|a Anti-Bacterial Agents
|2 NLM
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|a Soil
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|a Ciprofloxacin
|2 NLM
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|a Tetracycline
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|a Feng, Yu-Xi
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|4 aut
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|a Zhang, Hua
|e verfasserin
|4 aut
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700 |
1 |
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|a Yu, Xiao-Zhang
|e verfasserin
|4 aut
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773 |
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|i Enthalten in
|t Ecotoxicology (London, England)
|d 1992
|g 30(2021), 8 vom: 12. Okt., Seite 1598-1609
|w (DE-627)NLM098212214
|x 1573-3017
|7 nnas
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|g volume:30
|g year:2021
|g number:8
|g day:12
|g month:10
|g pages:1598-1609
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|u http://dx.doi.org/10.1007/s10646-020-02308-y
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