Investigation of pH-Responsiveness inside Lipid Nanoparticles for Parenteral mRNA Application Using Small-Angle X-ray Scattering
Messenger ribonucleic acid (mRNA)-based nanomedicines have shown to be a promising new lead in a broad field of potential applications such as tumor immunotherapy. Of these nanomedicines, lipid-based mRNA nanoparticles comprising ionizable lipids are gaining increasing attention as versatile technol...
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| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 36(2020), 44 vom: 10. Nov., Seite 13331-13341
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| 1. Verfasser: |
Uebbing, Lukas
(VerfasserIn) |
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| Weitere Verfasser: |
Ziller, Antje,
Siewert, Christian,
Schroer, Martin A,
Blanchet, Clement E,
Svergun, Dmitri I,
Ramishetti, Srinivas,
Peer, Dan,
Sahin, Ugur,
Haas, Heinrich,
Langguth, Peter |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2020
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
RNA, Messenger |
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