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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1002/adma.202003294
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|a pubmed25n1054.xml
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|a eng
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|a Soliman, Nancy
|e verfasserin
|4 aut
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|a Incorporation of Ru(II) Polypyridyl Complexes into Nanomaterials for Cancer Therapy and Diagnosis
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|c 2020
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|a Text
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|a ƒaComputermedien
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|a Date Completed 12.08.2021
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|a Date Revised 12.08.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a © 2020 Wiley-VCH GmbH.
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|a Ru(II) polypyridyl complexes are compounds of great interest in cancer therapy due to their unique photophysical, photochemical, and biological properties. For effective treatment, they must be able to penetrate tumor cells effectively and selectively. The development of nanoscale carriers capable of delivering Ru(II) polypyridyl complexes has the potential to passively or selectively enhance their cellular uptake in tumor cells. Many different strategies have been explored to incorporate Ru(II) polypyridyl complexes into a variety of nanosized constructs, ranging from organic to inorganic materials. Herein, recent developments in nanomaterials loaded with Ru(II) polypyridyl complexes are highlighted. Their rational design, preparation, and physicochemical properties are described, and their potential applications in cancer therapy are eventually discussed
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|a Journal Article
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|a Review
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|a anticancer
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|a medicinal inorganic chemistry
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|a metals in medicine
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|a nanomaterials
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|a nanomedicine
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|a Coordination Complexes
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|a Pyridines
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|a Ruthenium
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|a Gasser, Gilles
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|a Thomas, Christophe M
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|t Advanced materials (Deerfield Beach, Fla.)
|d 1998
|g 32(2020), 47 vom: 08. Nov., Seite e2003294
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|x 1521-4095
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|g volume:32
|g year:2020
|g number:47
|g day:08
|g month:11
|g pages:e2003294
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|u http://dx.doi.org/10.1002/adma.202003294
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