RNA polymerase II associated proteins regulate stomatal development through direct interaction with stomatal transcription factors in Arabidopsis thaliana

RNA polymerase II associated proteins regulate stomatal development through direct interaction with stomatal transcription factors in Arabidopsis thaliana

© 2020 The Authors New Phytologist © 2020 New Phytologist Foundation.

Bibliographische Detailangaben
Veröffentlicht in:The New phytologist. - 1979. - 230(2021), 1 vom: 15. Apr., Seite 171-189
1. Verfasser: Chen, Liang (VerfasserIn)
Weitere Verfasser: Zhao, Mingfeng, Wu, Zhongliang, Chen, Sicheng, Rojo, Enrique, Luo, Jiangwei, Li, Ping, Zhao, Lulu, Chen, Yan, Deng, Jianming, Cheng, Bo, He, Kai, Gou, Xiaoping, Li, Jia, Hou, Suiwen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2021
Zugriff auf das übergeordnete Werk:The New phytologist
Schlagworte:Journal Article Research Support, Non-U.S. Gov't IYO Pol II QQT1 RIMA RPAP stomata stomatal development transcriptional factor mehr... Arabidopsis Proteins Basic Helix-Loop-Helix Transcription Factors Transcription Factors RNA Polymerase II EC 2.7.7.-
Beschreibung
Zusammenfassung:© 2020 The Authors New Phytologist © 2020 New Phytologist Foundation.
RNA polymerase II (Pol II) associated proteins (RPAPs) have been ascribed diverse functions at the cellular level; however, their roles in developmental processes in yeasts, animals and plants are very poorly understood. Through screening for interactors of NRPB3, which encodes the third largest subunit of Pol II, we identified RIMA, the orthologue of mammalian RPAP2. A combination of genetic and biochemical assays revealed the role of RIMA and other RPAPs in stomatal development in Arabidopsis thaliana. We show that RIMA is involved in nuclear import of NRPB3 and other Pol II subunits, and is essential for restraining division and for establishing cell identity in the stomatal cell lineage. Moreover, plant RPAPs IYO/RPAP1 and QQT1/RPAP4, which interact with RIMA, are also crucial for stomatal development. Importantly, RIMA and QQT1 bind physically to stomatal transcription factors SPEECHLESS, MUTE, FAMA and SCREAMs. The RIMA-QQT1-IYO complex could work together with key stomatal transcription factors and Pol II to drive cell fate transitions in the stomatal cell lineage. Direct interactions with stomatal transcription factors provide a novel mechanism by which RPAP proteins may control differentiation of cell types and tissues in eukaryotes
Beschreibung:Date Completed 14.05.2021
Date Revised 31.05.2022
published: Print-Electronic
CommentIn: New Phytol. 2021 Apr;230(1):11-13. - PMID 33650186
Citation Status MEDLINE
ISSN:1469-8137
DOI:10.1111/nph.17004