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231225s2020 xx |||||o 00| ||eng c |
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|a 10.1016/j.clim.2020.108595
|2 doi
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|a pubmed24n1051.xml
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|a (DE-627)NLM315325143
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|a (NLM)32961330
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|a (PII)S1521-6616(20)30755-5
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Kakoullis, Loukas
|e verfasserin
|4 aut
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|a Infection-induced myeloperoxidase specific antineutrophil cytoplasmic antibody (MPO-ANCA) associated vasculitis
|b A systematic review
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|c 2020
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 14.05.2021
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|a Date Revised 14.05.2021
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a Copyright © 2020 Elsevier Inc. All rights reserved.
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|a BACKGROUND: We conducted a systematic review to identify cases of infection-induced anti-myeloperoxidase (MPO) antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV)
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|a METHODS: PubMed/Medline databases were searched from inception to July of 2020, according to PRISMA guidelines
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|a RESULTS: Among the 618 abstracts identified, 18 articles describing 23 patients (60.9% female, mean age 50.5 years) were included. Median time between infection and vasculitis development was 3 months. Five (21.7%) patients expired during follow-up. Vasculitis regressed after the resolution of infection in 12/23 (52.2%). ANCA titers decreased significantly on follow-up in 14/16 patients and in all survivors in which they were measured. Pathogens reported included Mycobacterium spp., Coccidioides spp., Rickettsia rickettsii, Staphylococcus spp., EBV, CMV and Dengue virus
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|a CONCLUSIONS: MPO-AAV can occur after infection and may regress after its resolution. Infection should be considered in cases of MPO-AAV, as immunosuppressive treatment can have catastrophic results if the infection is not adequately treated
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|a Journal Article
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|a Systematic Review
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|a Infection
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|a Microscopic polyangiitis
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|a Pathogenesis
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|a Vasculitis
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|a Virus
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|a Immunosuppressive Agents
|2 NLM
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|a Peroxidase
|2 NLM
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|a EC 1.11.1.7
|2 NLM
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1 |
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|a Parperis, Konstantinos
|e verfasserin
|4 aut
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1 |
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|a Papachristodoulou, Eleni
|e verfasserin
|4 aut
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|a Panos, George
|e verfasserin
|4 aut
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0 |
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|i Enthalten in
|t Clinical immunology (Orlando, Fla.)
|d 1999
|g 220(2020) vom: 01. Nov., Seite 108595
|w (DE-627)NLM098196855
|x 1521-7035
|7 nnns
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|g volume:220
|g year:2020
|g day:01
|g month:11
|g pages:108595
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|u http://dx.doi.org/10.1016/j.clim.2020.108595
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|a AR
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|d 220
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