Infection-induced myeloperoxidase specific antineutrophil cytoplasmic antibody (MPO-ANCA) associated vasculitis : A systematic review

Copyright © 2020 Elsevier Inc. All rights reserved.

Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 220(2020) vom: 01. Nov., Seite 108595
1. Verfasser: Kakoullis, Loukas (VerfasserIn)
Weitere Verfasser: Parperis, Konstantinos, Papachristodoulou, Eleni, Panos, George
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2020
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Systematic Review Infection Microscopic polyangiitis Pathogenesis Vasculitis Virus Immunosuppressive Agents Peroxidase EC 1.11.1.7
LEADER 01000naa a22002652 4500
001 NLM315325143
003 DE-627
005 20231225154653.0
007 cr uuu---uuuuu
008 231225s2020 xx |||||o 00| ||eng c
024 7 |a 10.1016/j.clim.2020.108595  |2 doi 
028 5 2 |a pubmed24n1051.xml 
035 |a (DE-627)NLM315325143 
035 |a (NLM)32961330 
035 |a (PII)S1521-6616(20)30755-5 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Kakoullis, Loukas  |e verfasserin  |4 aut 
245 1 0 |a Infection-induced myeloperoxidase specific antineutrophil cytoplasmic antibody (MPO-ANCA) associated vasculitis  |b A systematic review 
264 1 |c 2020 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 14.05.2021 
500 |a Date Revised 14.05.2021 
500 |a published: Print-Electronic 
500 |a Citation Status MEDLINE 
520 |a Copyright © 2020 Elsevier Inc. All rights reserved. 
520 |a BACKGROUND: We conducted a systematic review to identify cases of infection-induced anti-myeloperoxidase (MPO) antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) 
520 |a METHODS: PubMed/Medline databases were searched from inception to July of 2020, according to PRISMA guidelines 
520 |a RESULTS: Among the 618 abstracts identified, 18 articles describing 23 patients (60.9% female, mean age 50.5 years) were included. Median time between infection and vasculitis development was 3 months. Five (21.7%) patients expired during follow-up. Vasculitis regressed after the resolution of infection in 12/23 (52.2%). ANCA titers decreased significantly on follow-up in 14/16 patients and in all survivors in which they were measured. Pathogens reported included Mycobacterium spp., Coccidioides spp., Rickettsia rickettsii, Staphylococcus spp., EBV, CMV and Dengue virus 
520 |a CONCLUSIONS: MPO-AAV can occur after infection and may regress after its resolution. Infection should be considered in cases of MPO-AAV, as immunosuppressive treatment can have catastrophic results if the infection is not adequately treated 
650 4 |a Journal Article 
650 4 |a Systematic Review 
650 4 |a Infection 
650 4 |a Microscopic polyangiitis 
650 4 |a Pathogenesis 
650 4 |a Vasculitis 
650 4 |a Virus 
650 7 |a Immunosuppressive Agents  |2 NLM 
650 7 |a Peroxidase  |2 NLM 
650 7 |a EC 1.11.1.7  |2 NLM 
700 1 |a Parperis, Konstantinos  |e verfasserin  |4 aut 
700 1 |a Papachristodoulou, Eleni  |e verfasserin  |4 aut 
700 1 |a Panos, George  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Clinical immunology (Orlando, Fla.)  |d 1999  |g 220(2020) vom: 01. Nov., Seite 108595  |w (DE-627)NLM098196855  |x 1521-7035  |7 nnns 
773 1 8 |g volume:220  |g year:2020  |g day:01  |g month:11  |g pages:108595 
856 4 0 |u http://dx.doi.org/10.1016/j.clim.2020.108595  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_11 
912 |a GBV_ILN_24 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 220  |j 2020  |b 01  |c 11  |h 108595