|
|
|
|
| LEADER |
01000caa a22002652c 4500 |
| 001 |
NLM315092270 |
| 003 |
DE-627 |
| 005 |
20250228003703.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231225s2020 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1093/jxb/eraa433
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n1050.xml
|
| 035 |
|
|
|a (DE-627)NLM315092270
|
| 035 |
|
|
|a (NLM)32937656
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Liu, Xiaoxiao
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a RIN13-mediated disease resistance depends on the SNC1-EDS1/PAD4 signaling pathway in Arabidopsis
|
| 264 |
|
1 |
|c 2020
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 14.05.2021
|
| 500 |
|
|
|a Date Revised 31.05.2022
|
| 500 |
|
|
|a published: Print
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a © The Author(s) 2020. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissionsoup.com.
|
| 520 |
|
|
|a Plants have evolved an innate immune system to protect themselves from pathogen invasion with the help of intracellular nucleotide-binding leucine-rich repeat (NLR) receptors, though the mechanisms remain largely undefined. RIN13 (RPM1-interacting protein 13) was previously reported to enhance disease resistance, and suppress RPM1 (a CNL-type NLR)-mediated hypersensitive response in Arabidopsis via an as yet unknown mechanism. Here, we show that RIN13 is a nuclear-localized protein, and functions therein. Overexpression of RIN13 leads to autoimmunity with high accumulation of salicylic acid (SA), constitutive expression of pathogenesis-related genes, enhanced resistance to a virulent pathogen, and dwarfism. In addition, genetic and transcriptome analyses show that SA-dependent and SA-independent pathways are both required for RIN13-mediated disease resistance, with the EDS1/PAD4 complex as an integration point. RIN13-induced dwarfism was rescued completely by either the pad4-1 or the eds1-2 mutant but partially by snc1-r1, a mutant of the TNL gene SNC1, suggesting the involvement of EDS1/PAD4 and SNC1 in RIN13 functioning. Furthermore, transient expression assays indicated that RIN13 promotes the nuclear accumulation of PAD4. Collectively, our study uncovered a signaling pathway whereby SNC1 and EDS1/PAD4 act together to modulate RIN13-triggered plant defense responses
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
4 |
|a Research Support, Non-U.S. Gov't
|
| 650 |
|
4 |
|a Arabidopsis
|
| 650 |
|
4 |
|a EDS1
|
| 650 |
|
4 |
|a NLR
|
| 650 |
|
4 |
|a PAD4
|
| 650 |
|
4 |
|a RIN13
|
| 650 |
|
4 |
|a disease resistance
|
| 650 |
|
4 |
|a salicylic acid
|
| 650 |
|
7 |
|a Arabidopsis Proteins
|2 NLM
|
| 650 |
|
7 |
|a DNA-Binding Proteins
|2 NLM
|
| 650 |
|
7 |
|a EDS1 protein, Arabidopsis
|2 NLM
|
| 650 |
|
7 |
|a SNC1 protein, Arabidopsis
|2 NLM
|
| 650 |
|
7 |
|a Carboxylic Ester Hydrolases
|2 NLM
|
| 650 |
|
7 |
|a EC 3.1.1.-
|2 NLM
|
| 650 |
|
7 |
|a PAD4 protein, Arabidopsis
|2 NLM
|
| 650 |
|
7 |
|a EC 3.1.1.-
|2 NLM
|
| 650 |
|
7 |
|a Salicylic Acid
|2 NLM
|
| 650 |
|
7 |
|a O414PZ4LPZ
|2 NLM
|
| 700 |
1 |
|
|a Liu, Hui
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a He, Jingjing
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Zhang, Siyuan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Han, Hui
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Wang, Zhangying
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liu, Wen-Cheng
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Liang, Yun-Kuan
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Gao, Zhiyong
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of experimental botany
|d 1985
|g 71(2020), 22 vom: 31. Dez., Seite 7393-7404
|w (DE-627)NLM098182706
|x 1460-2431
|7 nnas
|
| 773 |
1 |
8 |
|g volume:71
|g year:2020
|g number:22
|g day:31
|g month:12
|g pages:7393-7404
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1093/jxb/eraa433
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 71
|j 2020
|e 22
|b 31
|c 12
|h 7393-7404
|